Ulrich P - Search Results

1

Nonclinical Development of Biologics: Integrating Safety, Pharmacokinetics, and Pharmacodynamics to Create Smarter and More Flexible Nonclinical Safety Programs Optimizing Animal Use.

Hey A, Baumann A, Kronenberg S, Blaich G, Mohl S, Fagg R, Ulrich P, Rattel B, Richter WF, Kiessling A, Weir L. Hey A, et al. Among authors: ulrich p. Int J Toxicol. 2021 May-Jun;40(3):270-284. doi: 10.1177/1091581821994288. Epub 2021 Feb 25. Int J Toxicol. 2021. PMID: 33631988

2

Nonclinical safety testing of biopharmaceuticals--Addressing current challenges of these novel and emerging therapies.

Brennan FR, Baumann A, Blaich G, de Haan L, Fagg R, Kiessling A, Kronenberg S, Locher M, Milton M, Tibbitts J, Ulrich P, Weir L. Brennan FR, et al. Among authors: ulrich p. Regul Toxicol Pharmacol. 2015 Oct;73(1):265-75. doi: 10.1016/j.yrtph.2015.07.019. Epub 2015 Jul 26. Regul Toxicol Pharmacol. 2015. PMID: 26219199

3

Biotherapeutics in non-clinical development: Strengthening the interface between safety, pharmacokinetics-pharmacodynamics and manufacturing.

Ulrich P, Blaich G, Baumann A, Fagg R, Hey A, Kiessling A, Kronenberg S, Lindecrona RH, Mohl S, Richter WF, Tibbitts J, Crameri F, Weir L. Ulrich P, et al. Regul Toxicol Pharmacol. 2018 Apr;94:91-100. doi: 10.1016/j.yrtph.2018.01.013. Epub 2018 Jan 28. Regul Toxicol Pharmacol. 2018. PMID: 29355662

4

Non-clinical Safety Evaluation of Biotherapeutics - Challenges, Opportunities and new Insights.

Blaich G, Baumann A, Kronenberg S, de Haan L, Ulrich P, Richter WF, Tibbitts J, Chivers S, Tarcsa E, Caldwell R, Crameri F. Blaich G, et al. Among authors: ulrich p. Regul Toxicol Pharmacol. 2016 Oct;80S:S1-S14. doi: 10.1016/j.yrtph.2016.08.012. Epub 2016 Aug 27. Regul Toxicol Pharmacol. 2016. PMID: 27578450

5

A modified murine local lymph node assay for the differentiation of contact photoallergy from phototoxicity by analysis of cytokine expression in skin-draining lymph node cells.

Ulrich P, Homey B, Vohr HW. Ulrich P, et al. Toxicology. 1998 Feb 6;125(2-3):149-68. doi: 10.1016/s0300-483x(97)00156-x. Toxicology. 1998. PMID: 9570330

6

Nonclinical Safety Assessment of CFZ533, a Fc-Silent Anti-CD40 Antibody, in Cynomolgus Monkeys.

Ulrich P, Flandre T, Espie P, Sickert D, Rubic-Schneider T, Shaw DA, Rush JS. Ulrich P, et al. Toxicol Sci. 2018 Nov 1;166(1):192-202. doi: 10.1093/toxsci/kfy196. Toxicol Sci. 2018. PMID: 30099540

7

Integrated preclinical photosafety testing strategy for systemically applied pharmaceuticals.

Schümann J, Boudon S, Ulrich P, Loll N, Garcia D, Schaffner R, Streich J, Kittel B, Bauer D. Schümann J, et al. Among authors: ulrich p. Toxicol Sci. 2014 May;139(1):245-56. doi: 10.1093/toxsci/kfu026. Epub 2014 Feb 11. Toxicol Sci. 2014. PMID: 24519524

8

Determination of the effect of calcineurin inhibitors on the rat's immune system after KLH immunisation.

Roman D, Ulrich P, Paul G, Court M, Vit P, Kehren J, Mahl A. Roman D, et al. Among authors: ulrich p. Toxicol Lett. 2004 Apr 1;149(1-3):133-40. doi: 10.1016/j.toxlet.2003.12.027. Toxicol Lett. 2004. PMID: 15093258

9

Contact allergens and irritants show discrete differences in the activation of human monocyte-derived dendritic cells: consequences for in vitro detection of contact allergens.

Straube F, Grenet O, Bruegger P, Ulrich P. Straube F, et al. Among authors: ulrich p. Arch Toxicol. 2005 Jan;79(1):37-46. doi: 10.1007/s00204-004-0606-8. Epub 2004 Sep 15. Arch Toxicol. 2005. PMID: 15372140

10

An European inter-laboratory validation of alternative endpoints of the murine local lymph node assay: 2nd round.

Ehling G, Hecht M, Heusener A, Huesler J, Gamer AO, van Loveren H, Maurer T, Riecke K, Ullmann L, Ulrich P, Vandebriel R, Vohr HW. Ehling G, et al. Among authors: ulrich p. Toxicology. 2005 Aug 15;212(1):69-79. doi: 10.1016/j.tox.2004.12.038. Epub 2005 Feb 12. Toxicology. 2005. PMID: 15878228

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