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The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer's disease.
Cheng-Hathaway PJ, Reed-Geaghan EG, Jay TR, Casali BT, Bemiller SM, Puntambekar SS, von Saucken VE, Williams RY, Karlo JC, Moutinho M, Xu G, Ransohoff RM, Lamb BT, Landreth GE. Cheng-Hathaway PJ, et al. Among authors: moutinho m. Mol Neurodegener. 2018 Jun 1;13(1):29. doi: 10.1186/s13024-018-0262-8. Mol Neurodegener. 2018. PMID: 29859094 Free PMC article.
Trem2 Y38C mutation and loss of Trem2 impairs neuronal synapses in adult mice.
Jadhav VS, Lin PBC, Pennington T, Di Prisco GV, Jannu AJ, Xu G, Moutinho M, Zhang J, Atwood BK, Puntambekar SS, Bissel SJ, Oblak AL, Landreth GE, Lamb BT. Jadhav VS, et al. Among authors: moutinho m. Mol Neurodegener. 2020 Oct 28;15(1):62. doi: 10.1186/s13024-020-00409-0. Mol Neurodegener. 2020. PMID: 33115519 Free PMC article.
67 results