Groves IJ - Search Results

1

Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention.

Groves IJ, Jackson SE, Poole EL, Nachshon A, Rozman B, Schwartz M, Prinjha RK, Tough DF, Sinclair JH, Wills MR. Groves IJ, et al. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2023025118. doi: 10.1073/pnas.2023025118. Proc Natl Acad Sci U S A. 2021. PMID: 33619107 Free PMC article.

2

Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter.

Woodhall DL, Groves IJ, Reeves MB, Wilkinson G, Sinclair JH. Woodhall DL, et al. Among authors: groves ij. J Biol Chem. 2006 Dec 8;281(49):37652-60. doi: 10.1074/jbc.M604273200. Epub 2006 Oct 11. J Biol Chem. 2006. PMID: 17035242 Free article.

3

Knockdown of hDaxx in normally non-permissive undifferentiated cells does not permit human cytomegalovirus immediate-early gene expression.

Groves IJ, Sinclair JH. Groves IJ, et al. J Gen Virol. 2007 Nov;88(Pt 11):2935-2940. doi: 10.1099/vir.0.83019-0. J Gen Virol. 2007. PMID: 17947514

4

NF-kappaB-mediated activation of the chemokine CCL22 by the product of the human cytomegalovirus gene UL144 escapes regulation by viral IE86.

Poole E, Atkins E, Nakayama T, Yoshie O, Groves I, Alcami A, Sinclair J. Poole E, et al. J Virol. 2008 May;82(9):4250-6. doi: 10.1128/JVI.02156-07. Epub 2008 Feb 20. J Virol. 2008. PMID: 18287226 Free PMC article.

5

Identification of TRIM23 as a cofactor involved in the regulation of NF-kappaB by human cytomegalovirus.

Poole E, Groves I, MacDonald A, Pang Y, Alcami A, Sinclair J. Poole E, et al. J Virol. 2009 Apr;83(8):3581-90. doi: 10.1128/JVI.02072-08. Epub 2009 Jan 28. J Virol. 2009. PMID: 19176615 Free PMC article.

6

Lytic infection of permissive cells with human cytomegalovirus is regulated by an intrinsic 'pre-immediate-early' repression of viral gene expression mediated by histone post-translational modification.

Groves IJ, Reeves MB, Sinclair JH. Groves IJ, et al. J Gen Virol. 2009 Oct;90(Pt 10):2364-2374. doi: 10.1099/vir.0.012526-0. Epub 2009 Jun 10. J Gen Virol. 2009. PMID: 19515830

7

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner.

Shan L, Li S, Meeldijk J, Blijenberg B, Hendriks A, van Boxtel KJWM, van den Berg SPH, Groves IJ, Potts M, Svrlanska A, Stamminger T, Wills MR, Bovenschen N. Shan L, et al. Among authors: groves ij. PLoS Pathog. 2020 Apr 13;16(4):e1008426. doi: 10.1371/journal.ppat.1008426. eCollection 2020 Apr. PLoS Pathog. 2020. PMID: 32282833 Free PMC article.

8

Human cytomegalovirus major immediate early transcripts arise predominantly from the canonical major immediate early promoter in reactivating progenitor-derived dendritic cells.

Mason R, Groves IJ, Wills MR, Sinclair JH, Reeves MB. Mason R, et al. Among authors: groves ij. J Gen Virol. 2020 Jun;101(6):635-644. doi: 10.1099/jgv.0.001419. J Gen Virol. 2020. PMID: 32375946 Free PMC article.

9

Bromodomain Inhibitors as Therapeutics for Herpesvirus-Related Disease: All BETs Are Off?

Groves IJ, Sinclair JH, Wills MR. Groves IJ, et al. Front Cell Infect Microbiol. 2020 Jul 2;10:329. doi: 10.3389/fcimb.2020.00329. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32714883 Free PMC article. Review.

10

Using Primary Human Cells to Analyze Human Cytomegalovirus Biology.

Poole E, Groves I, Jackson S, Wills M, Sinclair J. Poole E, et al. Methods Mol Biol. 2021;2244:51-81. doi: 10.1007/978-1-0716-1111-1_4. Methods Mol Biol. 2021. PMID: 33555582

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