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Deficiency of Endothelial CD40 Induces a Stable Plaque Phenotype and Limits Inflammatory Cell Recruitment to Atherosclerotic Lesions in Mice.
Gissler MC, Scherrer P, Anto-Michel N, Pennig J, Hoppe N, Füner L, Härdtner C, Stachon P, Li X, Mitre LS, Marchini T, Madl J, Wadle C, Hilgendorf I, von Zur Mühlen C, Bode C, Weber C, Lutgens E, Wolf D, Gerdes N, Zirlik A, Willecke F. Gissler MC, et al. Among authors: wolf d. Thromb Haemost. 2021 Nov;121(11):1530-1540. doi: 10.1055/a-1397-1858. Epub 2021 May 13. Thromb Haemost. 2021. PMID: 33618394
Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall.
Missiou A, Köstlin N, Varo N, Rudolf P, Aichele P, Ernst S, Münkel C, Walter C, Stachon P, Sommer B, Pfeifer D, Zirlik K, MacFarlane L, Wolf D, Tsitsikov E, Bode C, Libby P, Zirlik A. Missiou A, et al. Among authors: wolf d. Circulation. 2010 May 11;121(18):2033-44. doi: 10.1161/CIRCULATIONAHA.109.895037. Epub 2010 Apr 26. Circulation. 2010. PMID: 20421522 Free PMC article.
TRAF5 deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation.
Missiou A, Rudolf P, Stachon P, Wolf D, Varo N, Aichele P, Colberg C, Hoppe N, Ernst S, Münkel C, Walter C, Sommer B, Hilgendorf I, Nakano H, Bode C, Zirlik A. Missiou A, et al. Among authors: wolf d. Circ Res. 2010 Sep 17;107(6):757-66. doi: 10.1161/CIRCRESAHA.110.219295. Epub 2010 Jul 22. Circ Res. 2010. PMID: 20651286 Clinical Trial.
Cannabinoid receptor 2 signaling does not modulate atherogenesis in mice.
Willecke F, Zeschky K, Ortiz Rodriguez A, Colberg C, Auwärter V, Kneisel S, Hutter M, Lozhkin A, Hoppe N, Wolf D, von zur Mühlen C, Moser M, Hilgendorf I, Bode C, Zirlik A. Willecke F, et al. Among authors: wolf d. PLoS One. 2011 Apr 26;6(4):e19405. doi: 10.1371/journal.pone.0019405. PLoS One. 2011. PMID: 21541300 Free PMC article.
The oral spleen tyrosine kinase inhibitor fostamatinib attenuates inflammation and atherogenesis in low-density lipoprotein receptor-deficient mice.
Hilgendorf I, Eisele S, Remer I, Schmitz J, Zeschky K, Colberg C, Stachon P, Wolf D, Willecke F, Buchner M, Zirlik K, Ortiz-Rodriguez A, Lozhkin A, Hoppe N, von zur Muhlen C, zur Hausen A, Bode C, Zirlik A. Hilgendorf I, et al. Among authors: wolf d. Arterioscler Thromb Vasc Biol. 2011 Sep;31(9):1991-9. doi: 10.1161/ATVBAHA.111.230847. Epub 2011 Jun 23. Arterioscler Thromb Vasc Biol. 2011. PMID: 21700926
Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice.
Wolf D, Hohmann JD, Wiedemann A, Bledzka K, Blankenbach H, Marchini T, Gutte K, Zeschky K, Bassler N, Hoppe N, Rodriguez AO, Herr N, Hilgendorf I, Stachon P, Willecke F, Duerschmied D, von zur Muhlen C, Soloviev DA, Zhang L, Bode C, Plow EF, Libby P, Peter K, Zirlik A. Wolf D, et al. Circ Res. 2011 Nov 11;109(11):1269-79. doi: 10.1161/CIRCRESAHA.111.247684. Epub 2011 Oct 13. Circ Res. 2011. PMID: 21998326 Free PMC article.
CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies.
Wolf D, Jehle F, Ortiz Rodriguez A, Dufner B, Hoppe N, Colberg C, Lozhkin A, Bassler N, Rupprecht B, Wiedemann A, Hilgendorf I, Stachon P, Willecke F, Febbraio M, von zur Muhlen C, Binder CJ, Bode C, Zirlik A, Peter K. Wolf D, et al. PLoS One. 2012;7(3):e33026. doi: 10.1371/journal.pone.0033026. Epub 2012 Mar 8. PLoS One. 2012. PMID: 22412980 Free PMC article.
2,910 results