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MYB rearrangements and over-expression in T-cell acute lymphoblastic leukemia.
Bardelli V, Arniani S, Pierini V, Pierini T, Di Giacomo D, Gorello P, Moretti M, Pellanera F, Elia L, Vitale A, Storlazzi CT, Tolomeo D, Mastrodicasa E, Caniglia M, Chiaretti S, Ruggeri L, Roti G, Schwab C, Harrison CJ, Almeida A, Pieters T, Van Vlierberghe P, Mecucci C, La Starza R. Bardelli V, et al. Among authors: almeida a. Genes Chromosomes Cancer. 2021 Jul;60(7):482-488. doi: 10.1002/gcc.22943. Epub 2021 Mar 8. Genes Chromosomes Cancer. 2021. PMID: 33611795
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies.
Pieters T, T'Sas S, Demoen L, Almeida A, Haenebalcke L, Matthijssens F, Lemeire K, D'Hont J, Van Rockeghem F, Hochepied T, Lintermans B, Reunes L, Lammens T, Berx G, Haigh JJ, Goossens S, Van Vlierberghe P. Pieters T, et al. Among authors: almeida a. Sci Rep. 2019 Jul 22;9(1):10577. doi: 10.1038/s41598-019-46853-x. Sci Rep. 2019. PMID: 31332244 Free PMC article.
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
Pieters T, T'Sas S, Vanhee S, Almeida A, Driege Y, Roels J, Van Loocke W, Daneels W, Baens M, Marchand A, Van Trimpont M, Matthijssens F, Morscio J, Lemeire K, Lintermans B, Reunes L, Chaltin P, Offner F, Van Dorpe J, Hochepied T, Berx G, Beyaert R, Staal J, Van Vlierberghe P, Goossens S. Pieters T, et al. Among authors: almeida a. J Exp Med. 2021 Oct 4;218(10):e20202280. doi: 10.1084/jem.20202280. Epub 2021 Aug 18. J Exp Med. 2021. PMID: 34406363 Free PMC article.
Myb drives B-cell neoplasms and myeloid malignancies in vivo.
Pieters T, Almeida A, T'Sas S, Lemeire K, Hochepied T, Berx G, Kentsis A, Goossens S, Van Vlierberghe P. Pieters T, et al. Among authors: almeida a. Blood Adv. 2022 May 24;6(10):2987-2991. doi: 10.1182/bloodadvances.2021005955. Blood Adv. 2022. PMID: 35020834 Free PMC article. No abstract available.
Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia.
Almeida A, T'Sas S, Pagliaro L, Fijalkowski I, Sleeckx W, Van Steenberge H, Zamponi R, Lintermans B, Van Loocke W, Palhais B, Reekmans A, Bardelli V, Demoen L, Reunes L, Deforce D, Van Nieuwerburgh F, Kentsis A, Ntziachristos P, Van Roy N, De Moerloose B, Mecucci C, La Starza R, Roti G, Goossens S, Van Vlierberghe P, Pieters T. Almeida A, et al. Hemasphere. 2024 Mar 10;8(3):e51. doi: 10.1002/hem3.51. eCollection 2024 Mar. Hemasphere. 2024. PMID: 38463444 Free PMC article.
Cryo-EM analysis of complement C3 reveals a reversible major opening of the macroglobulin ring.
Gadeberg TAF, Jørgensen MH, Olesen HG, Lorentzen J, Harwood SL, Almeida AV, Fruergaard MU, Jensen RK, Kanis P, Pedersen H, Tranchant E, Petersen SV, Thøgersen IB, Kragelund BB, Lyons JA, Enghild JJ, Andersen GR. Gadeberg TAF, et al. Among authors: almeida av. Nat Struct Mol Biol. 2025 Jan 23. doi: 10.1038/s41594-024-01467-4. Online ahead of print. Nat Struct Mol Biol. 2025. PMID: 39849196
4,881 results