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Circadian time series proteomics reveals daily dynamics in cartilage physiology.
Dudek M, Angelucci C, Pathiranage D, Wang P, Mallikarjun V, Lawless C, Swift J, Kadler KE, Boot-Handford RP, Hoyland JA, Lamande SR, Bateman JF, Meng QJ. Dudek M, et al. Among authors: wang p. Osteoarthritis Cartilage. 2021 May;29(5):739-749. doi: 10.1016/j.joca.2021.02.008. Epub 2021 Feb 19. Osteoarthritis Cartilage. 2021. PMID: 33610821 Free PMC article.
The intervertebral disc contains intrinsic circadian clocks that are regulated by age and cytokines and linked to degeneration.
Dudek M, Yang N, Ruckshanthi JP, Williams J, Borysiewicz E, Wang P, Adamson A, Li J, Bateman JF, White MR, Boot-Handford RP, Hoyland JA, Meng QJ. Dudek M, et al. Among authors: wang p. Ann Rheum Dis. 2017 Mar;76(3):576-584. doi: 10.1136/annrheumdis-2016-209428. Epub 2016 Aug 3. Ann Rheum Dis. 2017. PMID: 27489225 Free PMC article.
The chondrocyte clock gene Bmal1 controls cartilage homeostasis and integrity.
Dudek M, Gossan N, Yang N, Im HJ, Ruckshanthi JP, Yoshitane H, Li X, Jin D, Wang P, Boudiffa M, Bellantuono I, Fukada Y, Boot-Handford RP, Meng QJ. Dudek M, et al. Among authors: wang p. J Clin Invest. 2016 Jan;126(1):365-76. doi: 10.1172/JCI82755. Epub 2015 Dec 14. J Clin Invest. 2016. PMID: 26657859 Free PMC article.
Functional and transcriptional profiling of non-coding RNAs in yeast reveal context-dependent phenotypes and in trans effects on the protein regulatory network.
Balarezo-Cisneros LN, Parker S, Fraczek MG, Timouma S, Wang P, O'Keefe RT, Millar CB, Delneri D. Balarezo-Cisneros LN, et al. Among authors: wang p. PLoS Genet. 2021 Jan 25;17(1):e1008761. doi: 10.1371/journal.pgen.1008761. eCollection 2021 Jan. PLoS Genet. 2021. PMID: 33493158 Free PMC article.
Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis.
Scott NA, Andrusaite A, Andersen P, Lawson M, Alcon-Giner C, Leclaire C, Caim S, Le Gall G, Shaw T, Connolly JPR, Roe AJ, Wessel H, Bravo-Blas A, Thomson CA, Kästele V, Wang P, Peterson DA, Bancroft A, Li X, Grencis R, Mowat AM, Hall LJ, Travis MA, Milling SWF, Mann ER. Scott NA, et al. Among authors: wang p. Sci Transl Med. 2018 Oct 24;10(464):eaao4755. doi: 10.1126/scitranslmed.aao4755. Sci Transl Med. 2018. PMID: 30355800 Free PMC article.
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