van der Es D - Search Results

1

Design and Characterization of an Intracellular Covalent Ligand for CC Chemokine Receptor 2.

Ortiz Zacarías NV, Chahal KK, Šimková T, van der Horst C, Zheng Y, Inoue A, Theunissen E, Mallee L, van der Es D, Louvel J, IJzerman AP, Handel TM, Kufareva I, Heitman LH. Ortiz Zacarías NV, et al. Among authors: van der es d, van der horst c. J Med Chem. 2021 Mar 11;64(5):2608-2621. doi: 10.1021/acs.jmedchem.0c01137. Epub 2021 Feb 18. J Med Chem. 2021. PMID: 33600174 Free PMC article.

2

Kinetics of human cannabinoid 1 (CB1) receptor antagonists: Structure-kinetics relationships (SKR) and implications for insurmountable antagonism.

Xia L, de Vries H, Yang X, Lenselink EB, Kyrizaki A, Barth F, Louvel J, Dreyer MK, van der Es D, IJzerman AP, Heitman LH. Xia L, et al. Among authors: van der es d. Biochem Pharmacol. 2018 May;151:166-179. doi: 10.1016/j.bcp.2017.10.014. Epub 2017 Nov 2. Biochem Pharmacol. 2018. PMID: 29102677 Free article.

3

An Affinity-Based Probe for the Human Adenosine A_2A Receptor.

Yang X, Michiels TJM, de Jong C, Soethoudt M, Dekker N, Gordon E, van der Stelt M, Heitman LH, van der Es D, IJzerman AP. Yang X, et al. Among authors: van der stelt m, van der es d. J Med Chem. 2018 Sep 13;61(17):7892-7901. doi: 10.1021/acs.jmedchem.8b00860. Epub 2018 Aug 21. J Med Chem. 2018. PMID: 30080404 Free PMC article.

4

Development of Covalent Ligands for G Protein-Coupled Receptors: A Case for the Human Adenosine A₃ Receptor.

Yang X, van Veldhoven JPD, Offringa J, Kuiper BJ, Lenselink EB, Heitman LH, van der Es D, IJzerman AP. Yang X, et al. Among authors: van der es d, van veldhoven jpd. J Med Chem. 2019 Apr 11;62(7):3539-3552. doi: 10.1021/acs.jmedchem.8b02026. Epub 2019 Mar 28. J Med Chem. 2019. PMID: 30869893 Free PMC article.

5

Design and pharmacological profile of a novel covalent partial agonist for the adenosine A₁ receptor.

Yang X, Dilweg MA, Osemwengie D, Burggraaff L, van der Es D, Heitman LH, IJzerman AP. Yang X, et al. Among authors: van der es d. Biochem Pharmacol. 2020 Oct;180:114144. doi: 10.1016/j.bcp.2020.114144. Epub 2020 Jul 10. Biochem Pharmacol. 2020. PMID: 32653590 Free article.

6

Molecular probes for the human adenosine receptors.

Yang X, Heitman LH, IJzerman AP, van der Es D. Yang X, et al. Among authors: van der es d. Purinergic Signal. 2021 Mar;17(1):85-108. doi: 10.1007/s11302-020-09753-8. Epub 2020 Dec 12. Purinergic Signal. 2021. PMID: 33313997 Free PMC article. Review.

7

Crystal Structure and Subsequent Ligand Design of a Nonriboside Partial Agonist Bound to the Adenosine A_2A Receptor.

Amelia T, van Veldhoven JPD, Falsini M, Liu R, Heitman LH, van Westen GJP, Segala E, Verdon G, Cheng RKY, Cooke RM, van der Es D, IJzerman AP. Amelia T, et al. Among authors: van westen gjp, van der es d, van veldhoven jpd. J Med Chem. 2021 Apr 8;64(7):3827-3842. doi: 10.1021/acs.jmedchem.0c01856. Epub 2021 Mar 25. J Med Chem. 2021. PMID: 33764785 Free PMC article.

8

Development of subtype-selective covalent ligands for the adenosine A_2B receptor by tuning the reactive group.

Beerkens BLH, Wang X, Avgeropoulou M, Adistia LN, van Veldhoven JPD, Jespers W, Liu R, Heitman LH, IJzerman AP, van der Es D. Beerkens BLH, et al. Among authors: van der es d. RSC Med Chem. 2022 Jun 21;13(7):850-856. doi: 10.1039/d2md00132b. eCollection 2022 Jul 20. RSC Med Chem. 2022. PMID: 35923720 Free PMC article.

9

A Chemical Biological Approach to Study G Protein-Coupled Receptors: Labeling the Adenosine A₁ Receptor Using an Electrophilic Covalent Probe.

Beerkens BLH, Koç Ç, Liu R, Florea BI, Le Dévédec SE, Heitman LH, IJzerman AP, van der Es D. Beerkens BLH, et al. Among authors: van der es d. ACS Chem Biol. 2022 Nov 18;17(11):3131-3139. doi: 10.1021/acschembio.2c00589. Epub 2022 Oct 24. ACS Chem Biol. 2022. PMID: 36279267 Free PMC article.

10

Development of an Affinity-Based Probe to Profile Endogenous Human Adenosine A₃ Receptor Expression.

Beerkens BLH, Snijders IM, Snoeck J, Liu R, Tool ATJ, Le Dévédec SE, Jespers W, Kuijpers TW, van Westen GJP, Heitman LH, IJzerman AP, van der Es D. Beerkens BLH, et al. Among authors: van der es d. J Med Chem. 2023 Aug 24;66(16):11399-11413. doi: 10.1021/acs.jmedchem.3c00854. Epub 2023 Aug 2. J Med Chem. 2023. PMID: 37531576 Free PMC article.

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