Tu X - Search Results

1

Inhibition of ATM Induces Hypersensitivity to Proton Irradiation by Upregulating Toxic End Joining.

Zhou Q, Howard ME, Tu X, Zhu Q, Denbeigh JM, Remmes NB, Herman MG, Beltran CJ, Yuan J, Greipp PT, Boughey JC, Wang L, Johnson N, Goetz MP, Sarkaria JN, Lou Z, Mutter RW. Zhou Q, et al. Among authors: tu x. Cancer Res. 2021 Jun 15;81(12):3333-3346. doi: 10.1158/0008-5472.CAN-20-2960. Epub 2021 Feb 17. Cancer Res. 2021. PMID: 33597272 Free PMC article.

2

USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization.

Wu C, Luo K, Zhao F, Yin P, Song Y, Deng M, Huang J, Chen Y, Li L, Lee S, Kim J, Zhou Q, Tu X, Nowsheen S, Luo Q, Gao X, Lou Z, Liu Z, Yuan J. Wu C, et al. Among authors: tu x. Cell Death Differ. 2018 Nov;25(10):1855-1869. doi: 10.1038/s41418-018-0138-z. Epub 2018 Jun 4. Cell Death Differ. 2018. PMID: 29867130 Free PMC article.

3

ATR Inhibition Is a Promising Radiosensitizing Strategy for Triple-Negative Breast Cancer.

Tu X, Kahila MM, Zhou Q, Yu J, Kalari KR, Wang L, Harmsen WS, Yuan J, Boughey JC, Goetz MP, Sarkaria JN, Lou Z, Mutter RW. Tu X, et al. Mol Cancer Ther. 2018 Nov;17(11):2462-2472. doi: 10.1158/1535-7163.MCT-18-0470. Epub 2018 Aug 30. Mol Cancer Ther. 2018. PMID: 30166399 Free PMC article.

4

USP39 regulates DNA damage response and chemo-radiation resistance by deubiquitinating and stabilizing CHK2.

Wu J, Chen Y, Geng G, Li L, Yin P, Nowsheen S, Li Y, Wu C, Liu J, Zhao F, Kim W, Zhou Q, Huang J, Guo G, Zhang C, Tu X, Gao X, Lou Z, Luo K, Qiao H, Yuan J. Wu J, et al. Among authors: tu x. Cancer Lett. 2019 May 1;449:114-124. doi: 10.1016/j.canlet.2019.02.015. Epub 2019 Feb 13. Cancer Lett. 2019. PMID: 30771428

5

UFL1 promotes histone H4 ufmylation and ATM activation.

Qin B, Yu J, Nowsheen S, Wang M, Tu X, Liu T, Li H, Wang L, Lou Z. Qin B, et al. Among authors: tu x. Nat Commun. 2019 Mar 18;10(1):1242. doi: 10.1038/s41467-019-09175-0. Nat Commun. 2019. PMID: 30886146 Free PMC article.

6

PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy.

Tu X, Qin B, Zhang Y, Zhang C, Kahila M, Nowsheen S, Yin P, Yuan J, Pei H, Li H, Yu J, Song Z, Zhou Q, Zhao F, Liu J, Zhang C, Dong H, Mutter RW, Lou Z. Tu X, et al. Mol Cell. 2019 Jun 20;74(6):1215-1226.e4. doi: 10.1016/j.molcel.2019.04.005. Epub 2019 Apr 30. Mol Cell. 2019. PMID: 31053471 Free PMC article.

7

A novel UCHL₃ inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair.

Song Z, Tu X, Zhou Q, Huang J, Chen Y, Liu J, Lee S, Kim W, Nowsheen S, Luo K, Yuan J, Lou Z. Song Z, et al. Among authors: tu x. Cell Death Dis. 2019 May 21;10(6):398. doi: 10.1038/s41419-019-1628-8. Cell Death Dis. 2019. PMID: 31113933 Free PMC article.

8

CHK2-FOXK axis promotes transcriptional control of autophagy programs.

Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, Nowsheen S, Wu C, Li Y, Li L, Kim W, Zhou Q, Huang J, Liu J, Zhang C, Guo G, Deng M, Tu X, Gao X, Liu Z, Chen Y, Lou Z, Luo K, Yuan J. Chen Y, et al. Among authors: tu x. Sci Adv. 2020 Jan 1;6(1):eaax5819. doi: 10.1126/sciadv.aax5819. eCollection 2020 Jan. Sci Adv. 2020. PMID: 31911943 Free PMC article.

9

Regulation of sister chromatid cohesion by nuclear PD-L1.

Yu J, Qin B, Moyer AM, Nowsheen S, Tu X, Dong H, Boughey JC, Goetz MP, Weinshilboum R, Lou Z, Wang L. Yu J, et al. Among authors: tu x. Cell Res. 2020 Jul;30(7):590-601. doi: 10.1038/s41422-020-0315-8. Epub 2020 Apr 29. Cell Res. 2020. PMID: 32350394 Free PMC article.

10

The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair.

Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, Zhang Y, Nowsheen S, Zhu Q, Deng M, Chen Y, Qin B, Luo K, Liu B, Lou Z, Mutter RW, Yuan J. Zhou Q, et al. Among authors: tu x. Nat Commun. 2020 May 26;11(1):2639. doi: 10.1038/s41467-020-16443-x. Nat Commun. 2020. PMID: 32457312 Free PMC article.

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