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Page 1
Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice.
Rome FI, Shobert GL, Voigt WC, Stagg DB, Puchalska P, Burgess SC, Crawford PA, Hughey CC. Rome FI, et al. Among authors: stagg db. Am J Physiol Endocrinol Metab. 2023 Jan 1;324(1):E9-E23. doi: 10.1152/ajpendo.00222.2022. Epub 2022 Nov 9. Am J Physiol Endocrinol Metab. 2023. PMID: 36351254 Free PMC article.
Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate.
Queathem ED, Stagg D, Nelson A, Chaves AB, Crown SB, Fulghum K, D Avignon DA, Ryder JR, Bolan PJ, Hayir A, Gillingham JR, Jannatpour S, Rome FI, Williams AS, Muoio DM, Ikramuddin S, Hughey CC, Puchalska P, Crawford PA. Queathem ED, et al. bioRxiv [Preprint]. 2024 Dec 21:2024.10.17.618895. doi: 10.1101/2024.10.17.618895. bioRxiv. 2024. PMID: 39464122 Free PMC article. Preprint.
Androgen receptor antagonism drives cytochrome P450 17A1 inhibitor efficacy in prostate cancer.
Norris JD, Ellison SJ, Baker JG, Stagg DB, Wardell SE, Park S, Alley HM, Baldi RM, Yllanes A, Andreano KJ, Stice JP, Lawrence SA, Eisner JR, Price DK, Moore WR, Figg WD, McDonnell DP. Norris JD, et al. Among authors: stagg db. J Clin Invest. 2017 Jun 1;127(6):2326-2338. doi: 10.1172/JCI87328. Epub 2017 May 2. J Clin Invest. 2017. PMID: 28463227 Free PMC article.
Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.
Pollock JA, Wardell SE, Parent AA, Stagg DB, Ellison SJ, Alley HM, Chao CA, Lawrence SA, Stice JP, Spasojevic I, Baker JG, Kim SH, McDonnell DP, Katzenellenbogen JA, Norris JD. Pollock JA, et al. Among authors: stagg db. Nat Chem Biol. 2016 Oct;12(10):795-801. doi: 10.1038/nchembio.2131. Epub 2016 Aug 8. Nat Chem Biol. 2016. PMID: 27501397 Free PMC article.
Small-Molecule-Mediated Degradation of the Androgen Receptor through Hydrophobic Tagging.
Gustafson JL, Neklesa TK, Cox CS, Roth AG, Buckley DL, Tae HS, Sundberg TB, Stagg DB, Hines J, McDonnell DP, Norris JD, Crews CM. Gustafson JL, et al. Among authors: stagg db. Angew Chem Int Ed Engl. 2015 Aug 10;54(33):9659-62. doi: 10.1002/anie.201503720. Epub 2015 Jun 17. Angew Chem Int Ed Engl. 2015. PMID: 26083457 Free PMC article.