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The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging.
McQuattie-Pimentel AC, Ren Z, Joshi N, Watanabe S, Stoeger T, Chi M, Lu Z, Sichizya L, Aillon RP, Chen CI, Soberanes S, Chen Z, Reyfman PA, Walter JM, Anekalla KR, Davis JM, Helmin KA, Runyan CE, Abdala-Valencia H, Nam K, Meliton AY, Winter DR, Morimoto RI, Mutlu GM, Bharat A, Perlman H, Gottardi CJ, Ridge KM, Chandel NS, Sznajder JI, Balch WE, Singer BD, Misharin AV, Budinger GRS. McQuattie-Pimentel AC, et al. Among authors: meliton ay. J Clin Invest. 2021 Feb 15;131(4):e140299. doi: 10.1172/JCI140299. J Clin Invest. 2021. PMID: 33586677 Free PMC article.
Transforming Growth Factor (TGF)-β Promotes de Novo Serine Synthesis for Collagen Production.
Nigdelioglu R, Hamanaka RB, Meliton AY, O'Leary E, Witt LJ, Cho T, Sun K, Bonham C, Wu D, Woods PS, Husain AN, Wolfgeher D, Dulin NO, Chandel NS, Mutlu GM. Nigdelioglu R, et al. Among authors: meliton ay. J Biol Chem. 2016 Dec 30;291(53):27239-27251. doi: 10.1074/jbc.M116.756247. Epub 2016 Nov 11. J Biol Chem. 2016. PMID: 27836973 Free PMC article.
Inhibition of Phosphoglycerate Dehydrogenase Attenuates Bleomycin-induced Pulmonary Fibrosis.
Hamanaka RB, Nigdelioglu R, Meliton AY, Tian Y, Witt LJ, O'Leary E, Sun KA, Woods PS, Wu D, Ansbro B, Ard S, Rohde JM, Dulin NO, Guzy RD, Mutlu GM. Hamanaka RB, et al. Among authors: meliton ay. Am J Respir Cell Mol Biol. 2018 May;58(5):585-593. doi: 10.1165/rcmb.2017-0186OC. Am J Respir Cell Mol Biol. 2018. PMID: 29019702 Free PMC article.
Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.
Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS. Soberanes S, et al. Among authors: meliton ay. Cell Metab. 2019 Feb 5;29(2):335-347.e5. doi: 10.1016/j.cmet.2018.09.019. Epub 2018 Oct 11. Cell Metab. 2019. PMID: 30318339 Free PMC article.
65 results