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Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells.
Crittenden S, Goepp M, Pollock J, Robb CT, Smyth DJ, Zhou Y, Andrews R, Tyrrell V, Gkikas K, Adima A, O'Connor RA, Davies L, Li XF, Yao HX, Ho GT, Zheng X, Mair A, Vermeren S, Qian BZ, Mole DJ, Gerasimidis K, Schwarze JKJ, Breyer RM, Arends MJ, O'Donnell VB, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Rossi AG, Howie SE, Yao C. Crittenden S, et al. Sci Adv. 2021 Feb 12;7(7):eabd7954. doi: 10.1126/sciadv.abd7954. Print 2021 Feb. Sci Adv. 2021. PMID: 33579710 Free PMC article.
Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.
Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, Mole DJ, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Ghazal P, Howie SE, Rossi AG, Yao C. Duffin R, et al. Among authors: crittenden s. Science. 2016 Mar 18;351(6279):1333-8. doi: 10.1126/science.aad9903. Science. 2016. PMID: 26989254 Free PMC article.
Prostaglandin E2 stimulates adaptive IL-22 production and promotes allergic contact dermatitis.
Robb CT, McSorley HJ, Lee J, Aoki T, Yu C, Crittenden S, Astier A, Felton JM, Parkinson N, Ayele A, Breyer RM, Anderton SM, Narumiya S, Rossi AG, Howie SE, Guttman-Yassky E, Weller RB, Yao C. Robb CT, et al. Among authors: crittenden s. J Allergy Clin Immunol. 2018 Jan;141(1):152-162. doi: 10.1016/j.jaci.2017.04.045. Epub 2017 Jun 3. J Allergy Clin Immunol. 2018. PMID: 28583370 Free PMC article.
A higher order PUF complex is central to regulation of C. elegans germline stem cells.
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Hall TMT. Qiu C, et al. Among authors: crittenden sl. Nat Commun. 2025 Jan 2;16(1):123. doi: 10.1038/s41467-024-55526-x. Nat Commun. 2025. PMID: 39747099 Free PMC article.
Mutation of GLP-1/Notch RAM domain results in a strong Glp-1 phenotype.
Crittenden SL, Dos Santos SJC, Battula S, Kimble J. Crittenden SL, et al. MicroPubl Biol. 2024 Nov 7;2024:10.17912/micropub.biology.001391. doi: 10.17912/micropub.biology.001391. eCollection 2024. MicroPubl Biol. 2024. PMID: 39583580 Free PMC article.
A higher order PUF complex is central to regulation of C. elegans germline stem cells.
Qiu C, Crittenden SL, Carrick BH, Dillard LB, Costa Dos Santos SJ, Dandey VP, Dutcher RC, Viverette EG, Wine RN, Woodworth J, Campbell ZT, Wickens M, Borgnia MJ, Kimble J, Tanaka Hall TM. Qiu C, et al. Among authors: crittenden sl. bioRxiv [Preprint]. 2024 Jun 14:2024.06.14.599074. doi: 10.1101/2024.06.14.599074. bioRxiv. 2024. Update in: Nat Commun. 2025 Jan 2;16(1):123. doi: 10.1038/s41467-024-55526-x PMID: 38915480 Free PMC article. Updated. Preprint.
69 results