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Combating Multidrug-Resistant Bacteria by Integrating a Novel Target Site Penetration and Receptor Binding Assay Platform Into Translational Modeling.
Lang Y, Shah NR, Tao X, Reeve SM, Zhou J, Moya B, Sayed ARM, Dharuman S, Oyer JL, Copik AJ, Fleischer BA, Shin E, Werkman C, Basso KB, Deveson Lucas D, Sutaria DS, Mégroz M, Kim TH, Loudon-Hossler V, Wright A, Jimenez-Nieves RH, Wallace MJ, Cadet KC, Jiao Y, Boyce JD, LoVullo ED, Schweizer HP, Bonomo RA, Bharatham N, Tsuji BT, Landersdorfer CB, Norris MH, Soo Shin B, Louie A, Balasubramanian V, Lee RE, Drusano GL, Bulitta JB. Lang Y, et al. Among authors: bonomo ra. Clin Pharmacol Ther. 2021 Apr;109(4):1000-1020. doi: 10.1002/cpt.2205. Epub 2021 Mar 24. Clin Pharmacol Ther. 2021. PMID: 33576025 Free PMC article.
In memoriam: John P. Quinn, MD.
Perez F, Arias CA, Bush K, Drusano GL, Lolans K, Munoz-Price LS, Nicolau DP, Queenan AM, Rice LB, Segreti J, Shlaes DM, Weinstein RA, Bonomo RA. Perez F, et al. Among authors: bonomo ra. Clin Infect Dis. 2014 Mar;58(5):748-50. doi: 10.1093/cid/cit801. Epub 2013 Dec 12. Clin Infect Dis. 2014. PMID: 24336826 Free PMC article. No abstract available.
Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa.
Winkler ML, Papp-Wallace KM, Hujer AM, Domitrovic TN, Hujer KM, Hurless KN, Tuohy M, Hall G, Bonomo RA. Winkler ML, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2015 Feb;59(2):1020-9. doi: 10.1128/AAC.04238-14. Epub 2014 Dec 1. Antimicrob Agents Chemother. 2015. PMID: 25451057 Free PMC article.
Exposing a β-Lactamase "Twist": the Mechanistic Basis for the High Level of Ceftazidime Resistance in the C69F Variant of the Burkholderia pseudomallei PenI β-Lactamase.
Papp-Wallace KM, Becka SA, Taracila MA, Winkler ML, Gatta JA, Rholl DA, Schweizer HP, Bonomo RA. Papp-Wallace KM, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2015 Nov 23;60(2):777-88. doi: 10.1128/AAC.02073-15. Print 2016 Feb. Antimicrob Agents Chemother. 2015. PMID: 26596949 Free PMC article.
Membrane-Bound PenA β-Lactamase of Burkholderia pseudomallei.
Randall LB, Dobos K, Papp-Wallace KM, Bonomo RA, Schweizer HP. Randall LB, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1509-14. doi: 10.1128/AAC.02444-15. Antimicrob Agents Chemother. 2015. PMID: 26711764 Free PMC article.
WCK 5107 (Zidebactam) and WCK 5153 Are Novel Inhibitors of PBP2 Showing Potent "β-Lactam Enhancer" Activity against Pseudomonas aeruginosa, Including Multidrug-Resistant Metallo-β-Lactamase-Producing High-Risk Clones.
Moya B, Barcelo IM, Bhagwat S, Patel M, Bou G, Papp-Wallace KM, Bonomo RA, Oliver A. Moya B, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2017 May 24;61(6):e02529-16. doi: 10.1128/AAC.02529-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28289035 Free PMC article.
Therapies for multidrug resistant and extensively drug-resistant non-fermenting gram-negative bacteria causing nosocomial infections: a perilous journey toward 'molecularly targeted' therapy.
El Chakhtoura NG, Saade E, Iovleva A, Yasmin M, Wilson B, Perez F, Bonomo RA. El Chakhtoura NG, et al. Among authors: bonomo ra. Expert Rev Anti Infect Ther. 2018 Feb;16(2):89-110. doi: 10.1080/14787210.2018.1425139. Epub 2018 Jan 16. Expert Rev Anti Infect Ther. 2018. PMID: 29310479 Free PMC article. Review.
758 results