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Page 1
Genetically modified immune cells targeting tumor antigens.
Poorebrahim M, Abazari MF, Sadeghi S, Mahmoudi R, Kheirollahi A, Askari H, Wickström SL, Poortahmasebi V, Lundqvist A, Kiessling R, Cid-Arregui A. Poorebrahim M, et al. Among authors: wickstrom sl. Pharmacol Ther. 2020 Oct;214:107603. doi: 10.1016/j.pharmthera.2020.107603. Epub 2020 Jun 15. Pharmacol Ther. 2020. PMID: 32553789 Free article. Review.
Visualization of human T lymphocyte-mediated eradication of cancer cells in vivo.
He X, Yin X, Wu J, Wickström SL, Duo Y, Du Q, Qin S, Yao S, Jing X, Hosaka K, Wu J, Jensen LD, Lundqvist A, Salter AI, Bräutigam L, Tao W, Chen Y, Kiessling R, Cao Y. He X, et al. Among authors: wickstrom sl. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):22910-22919. doi: 10.1073/pnas.2009092117. Epub 2020 Aug 28. Proc Natl Acad Sci U S A. 2020. PMID: 32859758 Free PMC article.
Complete and long-lasting clinical responses in immune checkpoint inhibitor-resistant, metastasized melanoma treated with adoptive T cell transfer combined with DC vaccination.
Lövgren T, Wolodarski M, Wickström S, Edbäck U, Wallin M, Martell E, Markland K, Blomberg P, Nyström M, Lundqvist A, Jacobsson H, Ullenhag G, Ljungman P, Hansson J, Masucci G, Tell R, Poschke I, Adamson L, Mattsson J, Kiessling R. Lövgren T, et al. Oncoimmunology. 2020 Jul 11;9(1):1792058. doi: 10.1080/2162402X.2020.1792058. Oncoimmunology. 2020. PMID: 32923156 Free PMC article. Clinical Trial.
Interleukin-33 is a Novel Immunosuppressor that Protects Cancer Cells from TIL Killing by a Macrophage-Mediated Shedding Mechanism.
Wu J, Chen Z, Wickström SL, Gao J, He X, Jing X, Wu J, Du Q, Yang M, Chen Y, Zhang D, Yin X, Guo Z, Jensen L, Yang Y, Tao W, Lundqvist A, Kiessling R, Cao Y. Wu J, et al. Among authors: wickstrom sl. Adv Sci (Weinh). 2021 Nov;8(21):e2101029. doi: 10.1002/advs.202101029. Epub 2021 Sep 5. Adv Sci (Weinh). 2021. PMID: 34486239 Free PMC article.
Tumor-associated NK cells drive MDSC-mediated tumor immune tolerance through the IL-6/STAT3 axis.
Neo SY, Tong L, Chong J, Liu Y, Jing X, Oliveira MMS, Chen Y, Chen Z, Lee K, Burduli N, Chen X, Gao J, Ma R, Lim JP, Huo J, Xu S, Alici E, Wickström SL, Haglund F, Hartman J, Wagner AK, Cao Y, Kiessling R, Lam KP, Westerberg LS, Lundqvist A. Neo SY, et al. Among authors: wickstrom sl. Sci Transl Med. 2024 May 15;16(747):eadi2952. doi: 10.1126/scitranslmed.adi2952. Epub 2024 May 15. Sci Transl Med. 2024. PMID: 38748775
Trogocytosis and fratricide killing impede MSLN-directed CAR T cell functionality.
Schoutrop E, Renken S, Micallef Nilsson I, Hahn P, Poiret T, Kiessling R, Wickström SL, Mattsson J, Magalhaes I. Schoutrop E, et al. Among authors: wickstrom sl. Oncoimmunology. 2022 Jun 28;11(1):2093426. doi: 10.1080/2162402X.2022.2093426. eCollection 2022. Oncoimmunology. 2022. PMID: 35898704 Free PMC article.
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