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Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates.
Slingsby MHL, Vijey P, Tsai IT, Roweth H, Couldwell G, Wilkie AR, Gaus H, Goolsby JM, Okazaki R, Terkovich BE, Semple JW, Thon JN, Henry SP, Narayanan P, Italiano JE Jr. Slingsby MHL, et al. Among authors: thon jn. Haematologica. 2022 Feb 1;107(2):519-531. doi: 10.3324/haematol.2020.260059. Haematologica. 2022. PMID: 33567808 Free PMC article.
Platelet formation.
Thon JN, Italiano JE. Thon JN, et al. Semin Hematol. 2010 Jul;47(3):220-6. doi: 10.1053/j.seminhematol.2010.03.005. Semin Hematol. 2010. PMID: 20620432 Free PMC article. Review.
Road blocks in making platelets for transfusion.
Thon JN, Medvetz DA, Karlsson SM, Italiano JE Jr. Thon JN, et al. J Thromb Haemost. 2015 Jun;13 Suppl 1(Suppl 1):S55-62. doi: 10.1111/jth.12942. J Thromb Haemost. 2015. PMID: 26149051 Free PMC article. Review.
Does size matter in platelet production?
Thon JN, Italiano JE Jr. Thon JN, et al. Blood. 2012 Aug 23;120(8):1552-61. doi: 10.1182/blood-2012-04-408724. Epub 2012 Jun 4. Blood. 2012. PMID: 22665937 Free PMC article. Review.
T granules in human platelets function in TLR9 organization and signaling.
Thon JN, Peters CG, Machlus KR, Aslam R, Rowley J, Macleod H, Devine MT, Fuchs TA, Weyrich AS, Semple JW, Flaumenhaft R, Italiano JE Jr. Thon JN, et al. J Cell Biol. 2012 Aug 20;198(4):561-74. doi: 10.1083/jcb.201111136. J Cell Biol. 2012. PMID: 22908309 Free PMC article.
Animating platelet production adds physiological context.
Thon JN, Kitterman AC, Italiano JE Jr. Thon JN, et al. Trends Mol Med. 2013 Oct;19(10):583-5. doi: 10.1016/j.molmed.2013.07.010. Epub 2013 Aug 14. Trends Mol Med. 2013. PMID: 23953478 Free PMC article.
41 results