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Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates.
Slingsby MHL, Vijey P, Tsai IT, Roweth H, Couldwell G, Wilkie AR, Gaus H, Goolsby JM, Okazaki R, Terkovich BE, Semple JW, Thon JN, Henry SP, Narayanan P, Italiano JE Jr. Slingsby MHL, et al. Haematologica. 2022 Feb 1;107(2):519-531. doi: 10.3324/haematol.2020.260059. Haematologica. 2022. PMID: 33567808 Free PMC article.