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Clonal hematopoiesis before, during, and after human spaceflight.
Mencia-Trinchant N, MacKay MJ, Chin C, Afshinnekoo E, Foox J, Meydan C, Butler D, Mozsary C, Vernice NA, Darby C, Schatz MC, Bailey SM, Melnick AM, Guzman ML, Bolton K, Braunstein LZ, Garrett-Bakelman F, Levine RL, Hassane DC, Mason CE. Mencia-Trinchant N, et al. Among authors: guzman ml. Cell Rep. 2021 Feb 9;34(6):108740. doi: 10.1016/j.celrep.2021.108740. Cell Rep. 2021. PMID: 33567281 Free article. No abstract available.
Acute myelogenous leukemia stem cells: from Bench to Bedside.
Felipe Rico J, Hassane DC, Guzman ML. Felipe Rico J, et al. Among authors: guzman ml. Cancer Lett. 2013 Sep 10;338(1):4-9. doi: 10.1016/j.canlet.2012.05.034. Epub 2012 Jun 17. Cancer Lett. 2013. PMID: 22713929 Free PMC article. Review.
A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species.
Zong H, Gozman A, Caldas-Lopes E, Taldone T, Sturgill E, Brennan S, Ochiana SO, Gomes-DaGama EM, Sen S, Rodina A, Koren J 3rd, Becker MW, Rudin CM, Melnick A, Levine RL, Roboz GJ, Nimer SD, Chiosis G, Guzman ML. Zong H, et al. Among authors: guzman ml. Cell Rep. 2015 Dec 15;13(10):2159-73. doi: 10.1016/j.celrep.2015.10.073. Epub 2015 Nov 25. Cell Rep. 2015. PMID: 26628369 Free PMC article.
Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia.
Li S, Garrett-Bakelman FE, Chung SS, Sanders MA, Hricik T, Rapaport F, Patel J, Dillon R, Vijay P, Brown AL, Perl AE, Cannon J, Bullinger L, Luger S, Becker M, Lewis ID, To LB, Delwel R, Löwenberg B, Döhner H, Döhner K, Guzman ML, Hassane DC, Roboz GJ, Grimwade D, Valk PJ, D'Andrea RJ, Carroll M, Park CY, Neuberg D, Levine R, Melnick AM, Mason CE. Li S, et al. Among authors: guzman ml. Nat Med. 2016 Jul;22(7):792-9. doi: 10.1038/nm.4125. Epub 2016 Jun 20. Nat Med. 2016. PMID: 27322744 Free PMC article.
Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.
Glass JL, Hassane D, Wouters BJ, Kunimoto H, Avellino R, Garrett-Bakelman FE, Guryanova OA, Bowman R, Redlich S, Intlekofer AM, Meydan C, Qin T, Fall M, Alonso A, Guzman ML, Valk PJM, Thompson CB, Levine R, Elemento O, Delwel R, Melnick A, Figueroa ME. Glass JL, et al. Among authors: guzman ml. Cancer Discov. 2017 Aug;7(8):868-883. doi: 10.1158/2159-8290.CD-16-1032. Epub 2017 Apr 13. Cancer Discov. 2017. PMID: 28408400 Free PMC article.
Minimal residual disease in acute myelogenous leukemia.
Cruz NM, Mencia-Trinchant N, Hassane DC, Guzman ML. Cruz NM, et al. Among authors: guzman ml. Int J Lab Hematol. 2017 May;39 Suppl 1(Suppl 1):53-60. doi: 10.1111/ijlh.12670. Int J Lab Hematol. 2017. PMID: 28447422 Free PMC article. Review.
Rational Targeting of Cooperating Layers of the Epigenome Yields Enhanced Therapeutic Efficacy against AML.
Duy C, Teater M, Garrett-Bakelman FE, Lee TC, Meydan C, Glass JL, Li M, Hellmuth JC, Mohammad HP, Smitheman KN, Shih AH, Abdel-Wahab O, Tallman MS, Guzman ML, Muench D, Grimes HL, Roboz GJ, Kruger RG, Creasy CL, Paietta EM, Levine RL, Carroll M, Melnick AM. Duy C, et al. Among authors: guzman ml. Cancer Discov. 2019 Jul;9(7):872-889. doi: 10.1158/2159-8290.CD-19-0106. Epub 2019 May 10. Cancer Discov. 2019. PMID: 31076479 Free PMC article.
Clonal Hematopoiesis and Premalignant Diseases.
Kaner J, Desai P, Mencia-Trinchant N, Guzman ML, Roboz GJ, Hassane DC. Kaner J, et al. Among authors: guzman ml. Cold Spring Harb Perspect Med. 2020 Apr 1;10(4):a035675. doi: 10.1101/cshperspect.a035675. Cold Spring Harb Perspect Med. 2020. PMID: 31615870 Free PMC article. Review.
138 results