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Page 1
NRF2 Activation Confers Resistance to eIF4A Inhibitors in Cancer Therapy.
Sanghvi VR, Mohan P, Singh K, Cao L, Berishaj M, Wolfe AL, Schatz JH, Lailler N, de Stanchina E, Viale A, Wendel HG. Sanghvi VR, et al. Among authors: schatz jh. Cancers (Basel). 2021 Feb 5;13(4):639. doi: 10.3390/cancers13040639. Cancers (Basel). 2021. PMID: 33562682 Free PMC article.
The Eph-receptor A7 is a soluble tumor suppressor for follicular lymphoma.
Oricchio E, Nanjangud G, Wolfe AL, Schatz JH, Mavrakis KJ, Jiang M, Liu X, Bruno J, Heguy A, Olshen AB, Socci ND, Teruya-Feldstein J, Weis-Garcia F, Tam W, Shaknovich R, Melnick A, Himanen JP, Chaganti RS, Wendel HG. Oricchio E, et al. Among authors: schatz jh. Cell. 2011 Oct 28;147(3):554-64. doi: 10.1016/j.cell.2011.09.035. Cell. 2011. PMID: 22036564 Free PMC article.
Frequent disruption of the RB pathway in indolent follicular lymphoma suggests a new combination therapy.
Oricchio E, Ciriello G, Jiang M, Boice MH, Schatz JH, Heguy A, Viale A, de Stanchina E, Teruya-Feldstein J, Bouska A, McKeithan T, Sander C, Tam W, Seshan VE, Chan WC, Chaganti RS, Wendel HG. Oricchio E, et al. Among authors: schatz jh. J Exp Med. 2014 Jun 30;211(7):1379-91. doi: 10.1084/jem.20132120. Epub 2014 Jun 9. J Exp Med. 2014. PMID: 24913233 Free PMC article.
RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer.
Wolfe AL, Singh K, Zhong Y, Drewe P, Rajasekhar VK, Sanghvi VR, Mavrakis KJ, Jiang M, Roderick JE, Van der Meulen J, Schatz JH, Rodrigo CM, Zhao C, Rondou P, de Stanchina E, Teruya-Feldstein J, Kelliher MA, Speleman F, Porco JA Jr, Pelletier J, Rätsch G, Wendel HG. Wolfe AL, et al. Among authors: schatz jh. Nature. 2014 Sep 4;513(7516):65-70. doi: 10.1038/nature13485. Epub 2014 Jul 27. Nature. 2014. PMID: 25079319 Free PMC article.
Targeted mutational profiling of peripheral T-cell lymphoma not otherwise specified highlights new mechanisms in a heterogeneous pathogenesis.
Schatz JH, Horwitz SM, Teruya-Feldstein J, Lunning MA, Viale A, Huberman K, Socci ND, Lailler N, Heguy A, Dolgalev I, Migliacci JC, Pirun M, Palomba ML, Weinstock DM, Wendel HG. Schatz JH, et al. Leukemia. 2015 Jan;29(1):237-41. doi: 10.1038/leu.2014.261. Epub 2014 Sep 3. Leukemia. 2015. PMID: 25257991 Free PMC article. No abstract available.
Progress against follicular lymphoma.
Schatz JH, Oricchio E, Puvvada SD, Wendel HG. Schatz JH, et al. Curr Opin Hematol. 2013 Jul;20(4):320-6. doi: 10.1097/MOH.0b013e3283622ed6. Curr Opin Hematol. 2013. PMID: 23673338 Free PMC article. Review.
Discovery of an eIF4A Inhibitor with a Novel Mechanism of Action.
Zerio CJ, Cunningham TA, Tulino AS, Alimusa EA, Buckley TM, Moore KT, Dodson M, Wilson NC, Ambrose AJ, Shi T, Sivinski J, Essegian DJ, Zhang DD, Schürer SC, Schatz JH, Chapman E. Zerio CJ, et al. Among authors: schatz jh. J Med Chem. 2021 Nov 11;64(21):15727-15746. doi: 10.1021/acs.jmedchem.1c01014. Epub 2021 Oct 22. J Med Chem. 2021. PMID: 34676755 Free PMC article.
55 results