Brundel DH - Search Results

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Depolymerization of hyaluronan using PEGylated human recombinant hyaluronidase promotes nanoparticle tumor penetration.

Brundel DH, Feeney OM, Nowell CJ, Suys EJ, Gracia G, Kaminskas LM, McIntosh MM, Kang DW, Porter CJ. Brundel DH, et al. Nanomedicine (Lond). 2021 Feb;16(4):275-292. doi: 10.2217/nnm-2020-0433. Epub 2021 Feb 9. Nanomedicine (Lond). 2021. PMID: 33560142

Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats.

Styles IK, Feeney OM, Nguyen TH, Brundel DHS, Kang DW, Clift R, McIntosh MP, Porter CJH. Styles IK, et al. Among authors: brundel dhs. J Control Release. 2019 Dec 10;315:85-96. doi: 10.1016/j.jconrel.2019.10.040. Epub 2019 Oct 23. J Control Release. 2019. PMID: 31655131

Lymph-directed immunotherapy - Harnessing endogenous lymphatic distribution pathways for enhanced therapeutic outcomes in cancer.

Feeney OM, Gracia G, Brundel DHS, Trevaskis NL, Cao E, Kaminskas LM, Porter CJH. Feeney OM, et al. Among authors: brundel dhs. Adv Drug Deliv Rev. 2020;160:115-135. doi: 10.1016/j.addr.2020.10.002. Epub 2020 Oct 9. Adv Drug Deliv Rev. 2020. PMID: 33039497

Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs.

Suys EJA, Brundel DHS, Chalmers DK, Pouton CW, Porter CJH. Suys EJA, et al. Among authors: brundel dhs. J Control Release. 2021 Mar 10;331:45-61. doi: 10.1016/j.jconrel.2021.01.007. Epub 2021 Jan 12. J Control Release. 2021. PMID: 33450318

Prevalence of potential drug-drug interactions in cancer patients treated with oral anticancer drugs.

van Leeuwen RW, Brundel DH, Neef C, van Gelder T, Mathijssen RH, Burger DM, Jansman FG. van Leeuwen RW, et al. Among authors: brundel dh. Br J Cancer. 2013 Mar 19;108(5):1071-8. doi: 10.1038/bjc.2013.48. Epub 2013 Feb 14. Br J Cancer. 2013. PMID: 23412102 Free PMC article.

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