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Metalloprotease SPRTN/DVC1 Orchestrates Replication-Coupled DNA-Protein Crosslink Repair.
Vaz B, Popovic M, Newman JA, Fielden J, Aitkenhead H, Halder S, Singh AN, Vendrell I, Fischer R, Torrecilla I, Drobnitzky N, Freire R, Amor DJ, Lockhart PJ, Kessler BM, McKenna GW, Gileadi O, Ramadan K. Vaz B, et al. Among authors: newman ja. Mol Cell. 2016 Nov 17;64(4):704-719. doi: 10.1016/j.molcel.2016.09.032. Epub 2016 Oct 27. Mol Cell. 2016. PMID: 27871366 Free PMC article.
The SNM1A DNA repair nuclease.
Baddock HT, Yosaatmadja Y, Newman JA, Schofield CJ, Gileadi O, McHugh PJ. Baddock HT, et al. Among authors: newman ja. DNA Repair (Amst). 2020 Nov;95:102941. doi: 10.1016/j.dnarep.2020.102941. Epub 2020 Jul 31. DNA Repair (Amst). 2020. PMID: 32866775 Free PMC article. Review.
SNM1A is crucial for efficient repair of complex DNA breaks in human cells.
Swift LP, Lagerholm BC, Henderson LR, Ratnaweera M, Baddock HT, Sengerova B, Lee S, Cruz-Migoni A, Waithe D, Renz C, Ulrich HD, Newman JA, Schofield CJ, McHugh PJ. Swift LP, et al. Among authors: newman ja. Nat Commun. 2024 Jun 25;15(1):5392. doi: 10.1038/s41467-024-49583-5. Nat Commun. 2024. PMID: 38918391 Free PMC article.
RecQ helicases in DNA repair and cancer targets.
Newman JA, Gileadi O. Newman JA, et al. Essays Biochem. 2020 Oct 26;64(5):819-830. doi: 10.1042/EBC20200012. Essays Biochem. 2020. PMID: 33095241 Free PMC article. Review.
FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.
Rota IA, Handel AE, Maio S, Klein F, Dhalla F, Deadman ME, Cheuk S, Newman JA, Michaels YS, Zuklys S, Prevot N, Hublitz P, Charles PD, Gkazi AS, Adamopoulou E, Qasim W, Davies EG, Hanson I, Pagnamenta AT, Camps C, Dreau HM, White A, James K, Fischer R, Gileadi O, Taylor JC, Fulga T, Lagerholm BC, Anderson G, Sezgin E, Holländer GA. Rota IA, et al. Among authors: newman ja. Sci Adv. 2021 Dec 3;7(49):eabj9247. doi: 10.1126/sciadv.abj9247. Epub 2021 Dec 3. Sci Adv. 2021. PMID: 34860543 Free PMC article.
217 results