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Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.
Uprety R, Che T, Zaidi SA, Grinnell SG, Varga BR, Faouzi A, Slocum ST, Allaoa A, Varadi A, Nelson M, Bernhard SM, Kulko E, Le Rouzic V, Eans SO, Simons CA, Hunkele A, Subrath J, Pan YX, Javitch JA, McLaughlin JP, Roth BL, Pasternak GW, Katritch V, Majumdar S. Uprety R, et al. Among authors: pan yx. Elife. 2021 Feb 8;10:e56519. doi: 10.7554/eLife.56519. Elife. 2021. PMID: 33555255 Free PMC article.
Dissociation of affinity and efficacy in KOR-3 chimeras.
Pan YX, Xu J, Ryan-Moro J, Mathis J, Hom JS, Mei J, Pasternak GW. Pan YX, et al. FEBS Lett. 1996 Oct 21;395(2-3):207-10. doi: 10.1016/0014-5793(96)01023-x. FEBS Lett. 1996. PMID: 8898097 Free article.
420 results