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ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer.
Centenera MM, Scott JS, Machiels J, Nassar ZD, Miller DC, Zinonos I, Dehairs J, Burvenich IJG, Zadra G, Chetta PM, Bango C, Evergren E, Ryan NK, Gillis JL, Mah CY, Tieu T, Hanson AR, Carelli R, Bloch K, Panagopoulos V, Waelkens E, Derua R, Williams ED, Evdokiou A, Cifuentes-Rius A, Voelcker NH, Mills IG, Tilley WD, Scott AM, Loda M, Selth LA, Swinnen JV, Butler LM. Centenera MM, et al. Among authors: machiels j. Cancer Res. 2021 Apr 1;81(7):1704-1718. doi: 10.1158/0008-5472.CAN-20-2511. Epub 2021 Feb 5. Cancer Res. 2021. PMID: 33547161
De novo lipogenesis protects cancer cells from free radicals and chemotherapeutics by promoting membrane lipid saturation.
Rysman E, Brusselmans K, Scheys K, Timmermans L, Derua R, Munck S, Van Veldhoven PP, Waltregny D, Daniëls VW, Machiels J, Vanderhoydonc F, Smans K, Waelkens E, Verhoeven G, Swinnen JV. Rysman E, et al. Among authors: machiels j. Cancer Res. 2010 Oct 15;70(20):8117-26. doi: 10.1158/0008-5472.CAN-09-3871. Epub 2010 Sep 28. Cancer Res. 2010. PMID: 20876798
Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition.
Butler LM, Mah CY, Machiels J, Vincent AD, Irani S, Mutuku SM, Spotbeen X, Bagadi M, Waltregny D, Moldovan M, Dehairs J, Vanderhoydonc F, Bloch K, Das R, Stahl J, Kench JG, Gevaert T, Derua R, Waelkens E, Nassar ZD, Selth LA, Trim PJ, Snel MF, Lynn DJ, Tilley WD, Horvath LG, Centenera MM, Swinnen JV. Butler LM, et al. Among authors: machiels j. Cancer Res. 2021 Oct 1;81(19):4981-4993. doi: 10.1158/0008-5472.CAN-20-3863. Epub 2021 Aug 6. Cancer Res. 2021. PMID: 34362796
Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma.
Marien E, Meister M, Muley T, Gomez Del Pulgar T, Derua R, Spraggins JM, Van de Plas R, Vanderhoydonc F, Machiels J, Binda MM, Dehairs J, Willette-Brown J, Hu Y, Dienemann H, Thomas M, Schnabel PA, Caprioli RM, Lacal JC, Waelkens E, Swinnen JV. Marien E, et al. Among authors: machiels j. Oncotarget. 2016 Mar 15;7(11):12582-97. doi: 10.18632/oncotarget.7179. Oncotarget. 2016. PMID: 26862848 Free PMC article.
The european organisation for research and treatment of cancer head and neck cancer module (EORTC QLQ-HN43): Estimates for minimal important difference and minimal important change.
Singer S, Hammerlid E, Tomaszewska IM, Amdal CD, Herlofson BB, Santos M, Castro Silva J, Mehanna H, Fullerton A, Young T, Fernandez Gonzalez L, Inhestern J, Pinto M, Arraras JI, Yarom N, Bonomo P, Baumann I, Galalae R, Nicolatou-Galitis O, Kiyota N, Raber-Durlacher J, Salem D, Fabian A, Boehm A, Krejovic-Trivic S, Chie WC, Taylor KJ, Sherman AC, Licitra L, Machiels JP, Bjordal K; EORTC Quality of Life Group and the EORTC Head and Neck Cancer Group. Singer S, et al. Among authors: machiels jp. Eur J Cancer. 2024 Oct 9;212:115062. doi: 10.1016/j.ejca.2024.115062. Online ahead of print. Eur J Cancer. 2024. PMID: 39405647
Trastuzumab Deruxtecan With Nivolumab in HER2-Expressing Metastatic Breast or Urothelial Cancer: Analysis of the Phase Ib DS8201-A-U105 Study.
Hamilton E, Galsky MD, Ochsenreither S, Del Conte G, Martín M, de Miguel MJ, Yu EY, Williams A, Gion M, Tan AR, Agrawal L, Rutten A, Machiels JP, Cresta S, Debruyne PR, Hennequin A, Moreno V, Minchom A, Valdes-Albini F, Petrylak D, Li L, Tsuchihashi Z, Suto F, Cheng FC, Kandil M, Barrios D, Hurvitz S. Hamilton E, et al. Among authors: machiels jp. Clin Cancer Res. 2024 Oct 15. doi: 10.1158/1078-0432.CCR-24-1513. Online ahead of print. Clin Cancer Res. 2024. PMID: 39405343
Association between antimicrobial usage in livestock and antimicrobial resistance in Escherichia coli isolates from human urinary tract infections in the Netherlands, 2009-2020.
Meijs AP, Chanamé-Pinedo LE, Deng H, Veldman KT, Brouwer MSM, van den Beld MJC, Dierikx CM, Sanders P, Wullings B, de Greeff SC, van Duijkeren E, Franz E, Pijnacker R, Mughini-Gras L; ISIS-AR study group. Meijs AP, et al. J Antimicrob Chemother. 2024 Oct 1;79(10):2622-2632. doi: 10.1093/jac/dkae268. J Antimicrob Chemother. 2024. PMID: 39092984
283 results