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Improved prediction of fracture risk leveraging a genome-wide polygenic risk score.
Lu T, Forgetta V, Keller-Baruch J, Nethander M, Bennett D, Forest M, Bhatnagar S, Walters RG, Lin K, Chen Z, Li L, Karlsson M, Mellström D, Orwoll E, McCloskey EV, Kanis JA, Leslie WD, Clarke RJ, Ohlsson C, Greenwood CMT, Richards JB. Lu T, et al. Among authors: karlsson m. Genome Med. 2021 Feb 3;13(1):16. doi: 10.1186/s13073-021-00838-6. Genome Med. 2021. PMID: 33536041 Free PMC article.
Limited clinical utility of a genetic risk score for the prediction of fracture risk in elderly subjects.
Eriksson J, Evans DS, Nielson CM, Shen J, Srikanth P, Hochberg M, McWeeney S, Cawthon PM, Wilmot B, Zmuda J, Tranah G, Mirel DB, Challa S, Mooney M, Crenshaw A, Karlsson M, Mellström D, Vandenput L, Orwoll E, Ohlsson C. Eriksson J, et al. Among authors: karlsson m. J Bone Miner Res. 2015 Jan;30(1):184-94. doi: 10.1002/jbmr.2314. J Bone Miner Res. 2015. PMID: 25043339 Free PMC article. Clinical Trial.
Increased Cortical Porosity in Older Men With Fracture.
Sundh D, Mellström D, Nilsson M, Karlsson M, Ohlsson C, Lorentzon M. Sundh D, et al. Among authors: karlsson m. J Bone Miner Res. 2015 Sep;30(9):1692-700. doi: 10.1002/jbmr.2509. Epub 2015 May 21. J Bone Miner Res. 2015. PMID: 25777580 Free article.
A Meta-Analysis of Trabecular Bone Score in Fracture Risk Prediction and Its Relationship to FRAX.
McCloskey EV, Odén A, Harvey NC, Leslie WD, Hans D, Johansson H, Barkmann R, Boutroy S, Brown J, Chapurlat R, Elders PJM, Fujita Y, Glüer CC, Goltzman D, Iki M, Karlsson M, Kindmark A, Kotowicz M, Kurumatani N, Kwok T, Lamy O, Leung J, Lippuner K, Ljunggren Ö, Lorentzon M, Mellström D, Merlijn T, Oei L, Ohlsson C, Pasco JA, Rivadeneira F, Rosengren B, Sornay-Rendu E, Szulc P, Tamaki J, Kanis JA. McCloskey EV, et al. Among authors: karlsson m. J Bone Miner Res. 2016 May;31(5):940-8. doi: 10.1002/jbmr.2734. Epub 2015 Nov 19. J Bone Miner Res. 2016. PMID: 26498132 Free article.
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.
Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB. Manousaki D, et al. Among authors: karlsson m. Am J Hum Genet. 2017 Aug 3;101(2):227-238. doi: 10.1016/j.ajhg.2017.06.014. Epub 2017 Jul 27. Am J Hum Genet. 2017. PMID: 28757204 Free PMC article.
High Serum Serotonin Predicts Increased Risk for Hip Fracture and Nonvertebral Osteoporotic Fractures: The MrOS Sweden Study.
Kristjansdottir HL, Lewerin C, Lerner UH, Waern E, Johansson H, Sundh D, Karlsson M, Cummings SR, Zetterberg H, Lorentzon M, Ohlsson C, Mellström D. Kristjansdottir HL, et al. Among authors: karlsson m. J Bone Miner Res. 2018 Sep;33(9):1560-1567. doi: 10.1002/jbmr.3443. Epub 2018 May 11. J Bone Miner Res. 2018. PMID: 29750841 Free article.
2,313 results