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Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Bernasocchi T, El Tekle G, Bolis M, Mutti A, Vallerga A, Brandt LP, Spriano F, Svinkina T, Zoma M, Ceserani V, Rinaldi A, Janouskova H, Bossi D, Cavalli M, Mosole S, Geiger R, Dong Z, Yang CG, Albino D, Rinaldi A, Schraml P, Linder S, Carbone GM, Alimonti A, Bertoni F, Moch H, Carr SA, Zwart W, Kruithof-de Julio M, Rubin MA, Udeshi ND, Theurillat JP. Bernasocchi T, et al. Among authors: zwart w. Nat Commun. 2021 Feb 2;12(1):734. doi: 10.1038/s41467-020-20820-x. Nat Commun. 2021. PMID: 33531470 Free PMC article.
Androgen receptor profiling predicts prostate cancer outcome.
Stelloo S, Nevedomskaya E, van der Poel HG, de Jong J, van Leenders GJ, Jenster G, Wessels LF, Bergman AM, Zwart W. Stelloo S, et al. Among authors: zwart w. EMBO Mol Med. 2015 Nov;7(11):1450-64. doi: 10.15252/emmm.201505424. EMBO Mol Med. 2015. PMID: 26412853 Free PMC article.
Integrative epigenetic taxonomy of primary prostate cancer.
Stelloo S, Nevedomskaya E, Kim Y, Schuurman K, Valle-Encinas E, Lobo J, Krijgsman O, Peeper DS, Chang SL, Feng FY, Wessels LFA, Henrique R, Jerónimo C, Bergman AM, Zwart W. Stelloo S, et al. Among authors: zwart w. Nat Commun. 2018 Nov 21;9(1):4900. doi: 10.1038/s41467-018-07270-2. Nat Commun. 2018. PMID: 30464211 Free PMC article.
Optimized ChIP-seq method facilitates transcription factor profiling in human tumors.
Singh AA, Schuurman K, Nevedomskaya E, Stelloo S, Linder S, Droog M, Kim Y, Sanders J, van der Poel H, Bergman AM, Wessels LF, Zwart W. Singh AA, et al. Among authors: zwart w. Life Sci Alliance. 2018 Dec 28;2(1):e201800115. doi: 10.26508/lsa.201800115. eCollection 2019 Feb. Life Sci Alliance. 2018. PMID: 30620009 Free PMC article.
CHD1 Loss Alters AR Binding at Lineage-Specific Enhancers and Modulates Distinct Transcriptional Programs to Drive Prostate Tumorigenesis.
Augello MA, Liu D, Deonarine LD, Robinson BD, Huang D, Stelloo S, Blattner M, Doane AS, Wong EWP, Chen Y, Rubin MA, Beltran H, Elemento O, Bergman AM, Zwart W, Sboner A, Dephoure N, Barbieri CE. Augello MA, et al. Among authors: zwart w. Cancer Cell. 2019 Apr 15;35(4):603-617.e8. doi: 10.1016/j.ccell.2019.03.001. Epub 2019 Mar 28. Cancer Cell. 2019. PMID: 30930119 Free PMC article.
The genomic landscape of metastatic castration-resistant prostate cancers reveals multiple distinct genotypes with potential clinical impact.
van Dessel LF, van Riet J, Smits M, Zhu Y, Hamberg P, van der Heijden MS, Bergman AM, van Oort IM, de Wit R, Voest EE, Steeghs N, Yamaguchi TN, Livingstone J, Boutros PC, Martens JWM, Sleijfer S, Cuppen E, Zwart W, van de Werken HJG, Mehra N, Lolkema MP. van Dessel LF, et al. Among authors: zwart w. Nat Commun. 2019 Nov 20;10(1):5251. doi: 10.1038/s41467-019-13084-7. Nat Commun. 2019. PMID: 31748536 Free PMC article.
181 results