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Page 1
Dual functions of SPOP and ERG dictate androgen therapy responses in prostate cancer.
Bernasocchi T, El Tekle G, Bolis M, Mutti A, Vallerga A, Brandt LP, Spriano F, Svinkina T, Zoma M, Ceserani V, Rinaldi A, Janouskova H, Bossi D, Cavalli M, Mosole S, Geiger R, Dong Z, Yang CG, Albino D, Rinaldi A, Schraml P, Linder S, Carbone GM, Alimonti A, Bertoni F, Moch H, Carr SA, Zwart W, Kruithof-de Julio M, Rubin MA, Udeshi ND, Theurillat JP. Bernasocchi T, et al. Among authors: geiger r. Nat Commun. 2021 Feb 2;12(1):734. doi: 10.1038/s41467-020-20820-x. Nat Commun. 2021. PMID: 33531470 Free PMC article.
Metabolic modulation of tumours with engineered bacteria for immunotherapy.
Canale FP, Basso C, Antonini G, Perotti M, Li N, Sokolovska A, Neumann J, James MJ, Geiger S, Jin W, Theurillat JP, West KA, Leventhal DS, Lora JM, Sallusto F, Geiger R. Canale FP, et al. Among authors: geiger s, geiger r. Nature. 2021 Oct;598(7882):662-666. doi: 10.1038/s41586-021-04003-2. Epub 2021 Oct 6. Nature. 2021. PMID: 34616044
Myc controls NK cell development, IL-15-driven expansion, and translational machinery.
Khameneh HJ, Fonta N, Zenobi A, Niogret C, Ventura P, Guerra C, Kwee I, Rinaldi A, Pecoraro M, Geiger R, Cavalli A, Bertoni F, Vivier E, Trumpp A, Guarda G. Khameneh HJ, et al. Among authors: geiger r. Life Sci Alliance. 2023 Apr 27;6(7):e202302069. doi: 10.26508/lsa.202302069. Print 2023 Jul. Life Sci Alliance. 2023. PMID: 37105715 Free PMC article.
Epigenome-wide impact of MAT2A sustains the androgen-indifferent state and confers synthetic vulnerability in ERG fusion-positive prostate cancer.
Cacciatore A, Shinde D, Musumeci C, Sandrini G, Guarrera L, Albino D, Civenni G, Storelli E, Mosole S, Federici E, Fusina A, Iozzo M, Rinaldi A, Pecoraro M, Geiger R, Bolis M, Catapano CV, Carbone GM. Cacciatore A, et al. Among authors: geiger r. Nat Commun. 2024 Aug 6;15(1):6672. doi: 10.1038/s41467-024-50908-7. Nat Commun. 2024. PMID: 39107274 Free PMC article.
A LAIR1 insertion generates broadly reactive antibodies against malaria variant antigens.
Tan J, Pieper K, Piccoli L, Abdi A, Perez MF, Geiger R, Tully CM, Jarrossay D, Maina Ndungu F, Wambua J, Bejon P, Fregni CS, Fernandez-Rodriguez B, Barbieri S, Bianchi S, Marsh K, Thathy V, Corti D, Sallusto F, Bull P, Lanzavecchia A. Tan J, et al. Among authors: geiger r. Nature. 2016 Jan 7;529(7584):105-109. doi: 10.1038/nature16450. Epub 2015 Dec 23. Nature. 2016. PMID: 26700814 Free PMC article.
Structural basis of malaria RIFIN binding by LILRB1-containing antibodies.
Chen Y, Xu K, Piccoli L, Foglierini M, Tan J, Jin W, Gorman J, Tsybovsky Y, Zhang B, Traore B, Silacci-Fregni C, Daubenberger C, Crompton PD, Geiger R, Sallusto F, Kwong PD, Lanzavecchia A. Chen Y, et al. Among authors: geiger r. Nature. 2021 Apr;592(7855):639-643. doi: 10.1038/s41586-021-03378-6. Epub 2021 Mar 31. Nature. 2021. PMID: 33790470 Free PMC article.
The roles of arginases and arginine in immunity.
Canè S, Geiger R, Bronte V. Canè S, et al. Among authors: geiger r. Nat Rev Immunol. 2024 Oct 17. doi: 10.1038/s41577-024-01098-2. Online ahead of print. Nat Rev Immunol. 2024. PMID: 39420221 Review.
A single T cell epitope drives the neutralizing anti-drug antibody response to natalizumab in multiple sclerosis patients.
Cassotta A, Mikol V, Bertrand T, Pouzieux S, Le Parc J, Ferrari P, Dumas J, Auer M, Deisenhammer F, Gastaldi M, Franciotta D, Silacci-Fregni C, Fernandez Rodriguez B, Giacchetto-Sasselli I, Foglierini M, Jarrossay D, Geiger R, Sallusto F, Lanzavecchia A, Piccoli L. Cassotta A, et al. Among authors: geiger r. Nat Med. 2019 Sep;25(9):1402-1407. doi: 10.1038/s41591-019-0568-2. Epub 2019 Sep 9. Nat Med. 2019. PMID: 31501610 Free PMC article.
384 results