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Whole-genome doubling confers unique genetic vulnerabilities on tumour cells.
Quinton RJ, DiDomizio A, Vittoria MA, Kotýnková K, Ticas CJ, Patel S, Koga Y, Vakhshoorzadeh J, Hermance N, Kuroda TS, Parulekar N, Taylor AM, Manning AL, Campbell JD, Ganem NJ. Quinton RJ, et al. Among authors: parulekar n. Nature. 2021 Feb;590(7846):492-497. doi: 10.1038/s41586-020-03133-3. Epub 2021 Jan 27. Nature. 2021. PMID: 33505027 Free PMC article.
A microbiota and dietary metabolite integrates DNA repair and cell death to regulate embryo viability and aneuploidy during aging.
Sonowal R, Swimm AI, Cingolani F, Parulekar N, Cleverley TL, Sahoo A, Ranawade A, Chaudhuri D, Mocarski ES, Koehler H, Nitsche K, Mesiano S, Kalman D. Sonowal R, et al. Among authors: parulekar n. Sci Adv. 2023 Feb 24;9(8):eade8653. doi: 10.1126/sciadv.ade8653. Epub 2023 Feb 24. Sci Adv. 2023. PMID: 36827370 Free PMC article.