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Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: ren p. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Triaryl pyrazoline compound inhibits flavivirus RNA replication.
Puig-Basagoiti F, Tilgner M, Forshey BM, Philpott SM, Espina NG, Wentworth DE, Goebel SJ, Masters PS, Falgout B, Ren P, Ferguson DM, Shi PY. Puig-Basagoiti F, et al. Among authors: ren p. Antimicrob Agents Chemother. 2006 Apr;50(4):1320-9. doi: 10.1128/AAC.50.4.1320-1329.2006. Antimicrob Agents Chemother. 2006. PMID: 16569847 Free PMC article.
A Rapid Zika Diagnostic Assay to Measure Neutralizing Antibodies in Patients.
Shan C, Xie X, Ren P, Loeffelholz MJ, Yang Y, Furuya A, Dupuis AP 2nd, Kramer LD, Wong SJ, Shi PY. Shan C, et al. Among authors: ren p. EBioMedicine. 2017 Mar;17:157-162. doi: 10.1016/j.ebiom.2017.03.006. Epub 2017 Mar 4. EBioMedicine. 2017. PMID: 28283425 Free PMC article.
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.
Xie X, Muruato AE, Zhang X, Lokugamage KG, Fontes-Garfias CR, Zou J, Liu J, Ren P, Balakrishnan M, Cihlar T, Tseng CK, Makino S, Menachery VD, Bilello JP, Shi PY. Xie X, et al. Among authors: ren p. bioRxiv [Preprint]. 2020 Jun 23:2020.06.22.165712. doi: 10.1101/2020.06.22.165712. bioRxiv. 2020. Update in: Nat Commun. 2020 Oct 15;11(1):5214. doi: 10.1038/s41467-020-19055-7 PMID: 32607511 Free PMC article. Updated. Preprint.
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: ren p. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.268854. doi: 10.1101/2020.08.26.268854. bioRxiv. 2020. Update in: Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4 PMID: 32869021 Free PMC article. Updated. Preprint.
1,950 results