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Page 1
Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.
Johnson BA, Xie X, Bailey AL, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Winkler ES, Swetnam D, Plante JA, Aguilar P, Plante KS, Popov V, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Diamond MS, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: lokugamage kg. Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4. Epub 2021 Jan 25. Nature. 2021. PMID: 33494095 Free PMC article.
Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. Among authors: lokugamage kg. Emerg Infect Dis. 2020 Jun;26(6):1266-1273. doi: 10.3201/eid2606.200516. Epub 2020 Jun 17. Emerg Infect Dis. 2020. PMID: 32160149 Free PMC article.
An Infectious cDNA Clone of SARS-CoV-2.
Xie X, Muruato A, Lokugamage KG, Narayanan K, Zhang X, Zou J, Liu J, Schindewolf C, Bopp NE, Aguilar PV, Plante KS, Weaver SC, Makino S, LeDuc JW, Menachery VD, Shi PY. Xie X, et al. Among authors: lokugamage kg. Cell Host Microbe. 2020 May 13;27(5):841-848.e3. doi: 10.1016/j.chom.2020.04.004. Epub 2020 Apr 13. Cell Host Microbe. 2020. PMID: 32289263 Free PMC article.
Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient.
Harcourt J, Tamin A, Lu X, Kamili S, Sakthivel SK, Murray J, Queen K, Tao Y, Paden CR, Zhang J, Li Y, Uehara A, Wang H, Goldsmith C, Bullock HA, Wang L, Whitaker B, Lynch B, Gautam R, Schindewolf C, Lokugamage KG, Scharton D, Plante JA, Mirchandani D, Widen SG, Narayanan K, Makino S, Ksiazek TG, Plante KS, Weaver SC, Lindstrom S, Tong S, Menachery VD, Thornburg NJ. Harcourt J, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2020 Mar 7:2020.03.02.972935. doi: 10.1101/2020.03.02.972935. bioRxiv. 2020. PMID: 32511316 Free PMC article. Preprint.
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19.
Xie X, Muruato AE, Zhang X, Lokugamage KG, Fontes-Garfias CR, Zou J, Liu J, Ren P, Balakrishnan M, Cihlar T, Tseng CK, Makino S, Menachery VD, Bilello JP, Shi PY. Xie X, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2020 Jun 23:2020.06.22.165712. doi: 10.1101/2020.06.22.165712. bioRxiv. 2020. Update in: Nat Commun. 2020 Oct 15;11(1):5214. doi: 10.1038/s41467-020-19055-7 PMID: 32607511 Free PMC article. Updated. Preprint.
Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis.
Johnson BA, Xie X, Kalveram B, Lokugamage KG, Muruato A, Zou J, Zhang X, Juelich T, Smith JK, Zhang L, Bopp N, Schindewolf C, Vu M, Vanderheiden A, Swetnam D, Plante JA, Aguilar P, Plante KS, Lee B, Weaver SC, Suthar MS, Routh AL, Ren P, Ku Z, An Z, Debbink K, Shi PY, Freiberg AN, Menachery VD. Johnson BA, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2020 Aug 26:2020.08.26.268854. doi: 10.1101/2020.08.26.268854. bioRxiv. 2020. Update in: Nature. 2021 Mar;591(7849):293-299. doi: 10.1038/s41586-021-03237-4 PMID: 32869021 Free PMC article. Updated. Preprint.
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.
Plante JA, Liu Y, Liu J, Xia H, Johnson BA, Lokugamage KG, Zhang X, Muruato AE, Zou J, Fontes-Garfias CR, Mirchandani D, Scharton D, Bilello JP, Ku Z, An Z, Kalveram B, Freiberg AN, Menachery VD, Xie X, Plante KS, Weaver SC, Shi PY. Plante JA, et al. Among authors: lokugamage kg. bioRxiv [Preprint]. 2020 Sep 2:2020.09.01.278689. doi: 10.1101/2020.09.01.278689. bioRxiv. 2020. Update in: Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3 PMID: 32908978 Free PMC article. Updated. Preprint.
Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.
Shi PY, Plante J, Liu Y, Liu J, Xia H, Johnson B, Lokugamage K, Zhang X, Muruato A, Zou J, Fontes-Garfias C, Mirchandani D, Scharton D, Kalveram B, Bilello J, Ku Z, An Z, Freiberg A, Menachery V, Xie X, Plante K, Weaver S. Shi PY, et al. Res Sq [Preprint]. 2020 Sep 10:rs.3.rs-70482. doi: 10.21203/rs.3.rs-70482/v1. Res Sq. 2020. Update in: Nature. 2021 Apr;592(7852):116-121. doi: 10.1038/s41586-020-2895-3 PMID: 32935091 Free PMC article. Updated. Preprint.
Type I Interferon Susceptibility Distinguishes SARS-CoV-2 from SARS-CoV.
Lokugamage KG, Hage A, de Vries M, Valero-Jimenez AM, Schindewolf C, Dittmann M, Rajsbaum R, Menachery VD. Lokugamage KG, et al. J Virol. 2020 Nov 9;94(23):e01410-20. doi: 10.1128/JVI.01410-20. Print 2020 Nov 9. J Virol. 2020. PMID: 32938761 Free PMC article.
50 results