Houk KN - Search Results

1

Isoquinoline thiosemicarbazone displays potent anticancer activity with in vivo efficacy against aggressive leukemias.

Sun DL, Poddar S, Pan RD, Rosser EW, Abt ER, Van Valkenburgh J, Le TM, Lok V, Hernandez SP, Song J, Li J, Turlik A, Chen X, Cheng CA, Chen W, Mona CE, Stuparu AD, Vergnes L, Reue K, Damoiseaux R, Zink JI, Czernin J, Donahue TR, Houk KN, Jung ME, Radu CG. Sun DL, et al. Among authors: houk kn. RSC Med Chem. 2020 Feb 24;11(3):392-410. doi: 10.1039/c9md00594c. eCollection 2020 Mar 1. RSC Med Chem. 2020. PMID: 33479645 Free PMC article.

2

Origins of stereoselectivity in intramolecular Diels-Alder cycloadditions of dienes and dienophiles linked by ester and amide tethers.

Tantillo DJ, Houk KN, Jung ME. Tantillo DJ, et al. Among authors: houk kn. J Org Chem. 2001 Mar 23;66(6):1938-40. doi: 10.1021/jo001172h. J Org Chem. 2001. PMID: 11300884

3

Theoretical elucidation of kinetic and thermodynamic control of radical addition regioselectivity.

Leach AG, Wang R, Wohlhieter GE, Khan SI, Jung ME, Houk KN. Leach AG, et al. Among authors: houk kn. J Am Chem Soc. 2003 Apr 9;125(14):4271-8. doi: 10.1021/ja029342q. J Am Chem Soc. 2003. PMID: 12670249

4

Unexpected syn hydride migration in the non-aldol aldol reaction.

Jung ME, van den Heuvel A, Leach AG, Houk KN. Jung ME, et al. Among authors: houk kn. Org Lett. 2003 Sep 18;5(19):3375-8. doi: 10.1021/ol0350801. Org Lett. 2003. PMID: 12967278

5

Synthesis and relative stability of 3,5-diacyl-4,5-dihydro-1H-pyrazoles prepared by dipolar cycloaddition of enones and alpha-diazoketones.

Jung ME, Min SJ, Houk KN, Ess D. Jung ME, et al. Among authors: houk kn. J Org Chem. 2004 Dec 24;69(26):9085-9. doi: 10.1021/jo048741w. J Org Chem. 2004. PMID: 15609941

6

Theoretical investigation of the stereoselective stepwise cope rearrangement of a 3-vinylmethylenecyclobutane.

Zhao YL, Suhrada CP, Jung ME, Houk KN. Zhao YL, et al. Among authors: houk kn. J Am Chem Soc. 2006 Aug 30;128(34):11106-13. doi: 10.1021/ja060913e. J Am Chem Soc. 2006. PMID: 16925428

7

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase.

Aghajan M, Jonai N, Flick K, Fu F, Luo M, Cai X, Ouni I, Pierce N, Tang X, Lomenick B, Damoiseaux R, Hao R, Del Moral PM, Verma R, Li Y, Li C, Houk KN, Jung ME, Zheng N, Huang L, Deshaies RJ, Kaiser P, Huang J. Aghajan M, et al. Among authors: houk kn. Nat Biotechnol. 2010 Jul;28(7):738-42. doi: 10.1038/nbt.1645. Epub 2010 Jun 27. Nat Biotechnol. 2010. PMID: 20581845 Free PMC article.

8

Synthesis of a trans,syn,trans-dodecahydrophenanthrene via a bicyclic transannular Diels-Alder reaction: intermediate for the synthesis of fusidic acid.

Jung ME, Zhang TH, Lui RM, Gutierrez O, Houk KN. Jung ME, et al. Among authors: houk kn. J Org Chem. 2010 Oct 15;75(20):6933-40. doi: 10.1021/jo101533h. J Org Chem. 2010. PMID: 20843028

9

Computational elucidation of the origins of reactivity and selectivity in non-aldol aldol rearrangements of cyclic epoxides.

Wang H, Houk KN, Allen DA, Jung ME. Wang H, et al. Among authors: houk kn. Org Lett. 2011 Jun 17;13(12):3238-41. doi: 10.1021/ol2011488. Epub 2011 May 13. Org Lett. 2011. PMID: 21568276 Free PMC article.

10

Palladium hydride promoted stereoselective isomerization of unactivated di(exo)methylenes to endocyclic dienes.

Jung ME, Lee GS, Pham HV, Houk KN. Jung ME, et al. Among authors: houk kn. Org Lett. 2014 May 2;16(9):2382-5. doi: 10.1021/ol500710v. Epub 2014 Apr 11. Org Lett. 2014. PMID: 24720691 Free PMC article.

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