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Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer.
Abril YLN, Fernandez IR, Hong JY, Chiang YL, Kutateladze DA, Zhao Q, Yang M, Hu J, Sadhukhan S, Li B, He B, Remick B, Bai JJ, Mullmann J, Wang F, Maymi V, Dhawan R, Auwerx J, Southard T, Cerione RA, Lin H, Weiss RS. Abril YLN, et al. Among authors: he b. Oncogene. 2021 Mar;40(9):1644-1658. doi: 10.1038/s41388-020-01637-w. Epub 2021 Jan 21. Oncogene. 2021. PMID: 33479498 Free PMC article.
A FRET-based assay for screening SIRT5 specific modulators.
Li Y, Huang W, You L, Xie T, He B. Li Y, et al. Among authors: he b. Bioorg Med Chem Lett. 2015 Apr 15;25(8):1671-1674. doi: 10.1016/j.bmcl.2015.03.018. Epub 2015 Mar 14. Bioorg Med Chem Lett. 2015. PMID: 25818461
SIRT4 is the last puzzle of mitochondrial sirtuins.
Li Y, Zhou Y, Wang F, Chen X, Wang C, Wang J, Liu T, Li Y, He B. Li Y, et al. Among authors: he b. Bioorg Med Chem. 2018 Aug 7;26(14):3861-3865. doi: 10.1016/j.bmc.2018.07.031. Epub 2018 Jul 19. Bioorg Med Chem. 2018. PMID: 30033389 Review.
A mini-review on Sirtuin activity assays.
Li Y, Liu T, Liao S, Li Y, Lan Y, Wang A, Wang Y, He B. Li Y, et al. Among authors: he b. Biochem Biophys Res Commun. 2015 Nov 20;467(3):459-66. doi: 10.1016/j.bbrc.2015.09.172. Epub 2015 Oct 9. Biochem Biophys Res Commun. 2015. PMID: 26456653 Review.
Identification of a cellularly active SIRT6 allosteric activator.
Huang Z, Zhao J, Deng W, Chen Y, Shang J, Song K, Zhang L, Wang C, Lu S, Yang X, He B, Min J, Hu H, Tan M, Xu J, Zhang Q, Zhong J, Sun X, Mao Z, Lin H, Xiao M, Chin YE, Jiang H, Xu Y, Chen G, Zhang J. Huang Z, et al. Among authors: he b. Nat Chem Biol. 2018 Dec;14(12):1118-1126. doi: 10.1038/s41589-018-0150-0. Epub 2018 Oct 29. Nat Chem Biol. 2018. PMID: 30374165
A FRET-based assay for screening SIRT6 modulators.
Li Y, You L, Huang W, Liu J, Zhu H, He B. Li Y, et al. Among authors: he b. Eur J Med Chem. 2015;96:245-9. doi: 10.1016/j.ejmech.2015.04.008. Epub 2015 Apr 9. Eur J Med Chem. 2015. PMID: 25884115
8,037 results