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99,497 results

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A Chinese hamster transcription start site atlas that enables targeted editing of CHO cells.
Shamie I, Duttke SH, Karottki KJC, Han CZ, Hansen AH, Hefzi H, Xiong K, Li S, Roth SJ, Tao J, Lee GM, Glass CK, Kildegaard HF, Benner C, Lewis NE. Shamie I, et al. Among authors: li s. NAR Genom Bioinform. 2021 Jul 13;3(3):lqab061. doi: 10.1093/nargab/lqab061. eCollection 2021 Sep. NAR Genom Bioinform. 2021. PMID: 34268494 Free PMC article.
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference.
Xiong K, Marquart KF, la Cour Karottki KJ, Li S, Shamie I, Lee JS, Gerling S, Yeo NC, Chavez A, Lee GM, Lewis NE, Kildegaard HF. Xiong K, et al. Among authors: li s. Biotechnol Bioeng. 2019 Jul;116(7):1813-1819. doi: 10.1002/bit.26969. Epub 2019 Apr 2. Biotechnol Bioeng. 2019. PMID: 30883679 Free PMC article.
Awakening dormant glycosyltransferases in CHO cells with CRISPRa.
Karottki KJC, Hefzi H, Xiong K, Shamie I, Hansen AH, Li S, Pedersen LE, Li S, Lee JS, Lee GM, Kildegaard HF, Lewis NE. Karottki KJC, et al. Among authors: li s. Biotechnol Bioeng. 2020 Feb;117(2):593-598. doi: 10.1002/bit.27199. Epub 2019 Nov 12. Biotechnol Bioeng. 2020. PMID: 31631317 Free PMC article.
Combating viral contaminants in CHO cells by engineering innate immunity.
Chiang AWT, Li S, Kellman BP, Chattopadhyay G, Zhang Y, Kuo CC, Gutierrez JM, Ghazi F, Schmeisser H, Ménard P, Bjørn SP, Voldborg BG, Rosenberg AS, Puig M, Lewis NE. Chiang AWT, et al. Among authors: li s. Sci Rep. 2019 Jun 20;9(1):8827. doi: 10.1038/s41598-019-45126-x. Sci Rep. 2019. PMID: 31222165 Free PMC article.
Model-based assessment of mammalian cell metabolic functionalities using omics data.
Richelle A, Kellman BP, Wenzel AT, Chiang AWT, Reagan T, Gutierrez JM, Joshi C, Li S, Liu JK, Masson H, Lee J, Li Z, Heirendt L, Trefois C, Juarez EF, Bath T, Borland D, Mesirov JP, Robasky K, Lewis NE. Richelle A, et al. Among authors: li s, li z. Cell Rep Methods. 2021 Jul 26;1(3):100040. doi: 10.1016/j.crmeth.2021.100040. Epub 2021 Jun 30. Cell Rep Methods. 2021. PMID: 34761247 Free PMC article.
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion.
Gutierrez JM, Feizi A, Li S, Kallehauge TB, Hefzi H, Grav LM, Ley D, Baycin Hizal D, Betenbaugh MJ, Voldborg B, Faustrup Kildegaard H, Min Lee G, Palsson BO, Nielsen J, Lewis NE. Gutierrez JM, et al. Among authors: li s. Nat Commun. 2020 Jan 2;11(1):68. doi: 10.1038/s41467-019-13867-y. Nat Commun. 2020. PMID: 31896772 Free PMC article.
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