Reiter JF - Search Results

1

Smoothened-activating lipids drive resistance to CDK4/6 inhibition in Hedgehog-associated medulloblastoma cells and preclinical models.

Daggubati V, Hochstelter J, Bommireddy A, Choudhury A, Krup AL, Kaur P, Tong P, Li A, Xu L, Reiter JF, Raleigh DR. Daggubati V, et al. Among authors: reiter jf. J Clin Invest. 2021 Mar 15;131(6):e141171. doi: 10.1172/JCI141171. J Clin Invest. 2021. PMID: 33476305 Free PMC article.

2

The primary cilium at the crossroads of mammalian hedgehog signaling.

Wong SY, Reiter JF. Wong SY, et al. Among authors: reiter jf. Curr Top Dev Biol. 2008;85:225-60. doi: 10.1016/S0070-2153(08)00809-0. Curr Top Dev Biol. 2008. PMID: 19147008 Free PMC article. Review.

3

Small molecule inhibitors of Smoothened ciliary localization and ciliogenesis.

Wu VM, Chen SC, Arkin MR, Reiter JF. Wu VM, et al. Among authors: reiter jf. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13644-9. doi: 10.1073/pnas.1207170109. Epub 2012 Aug 3. Proc Natl Acad Sci U S A. 2012. PMID: 22864913 Free PMC article.

4

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

Kodani A, Yu TW, Johnson JR, Jayaraman D, Johnson TL, Al-Gazali L, Sztriha L, Partlow JN, Kim H, Krup AL, Dammermann A, Krogan NJ, Walsh CA, Reiter JF. Kodani A, et al. Among authors: reiter jf. Elife. 2015 Aug 22;4:e07519. doi: 10.7554/eLife.07519. Elife. 2015. PMID: 26297806 Free PMC article.

5

Hedgehog signaling drives medulloblastoma growth via CDK6.

Raleigh DR, Choksi PK, Krup AL, Mayer W, Santos N, Reiter JF. Raleigh DR, et al. Among authors: reiter jf. J Clin Invest. 2018 Jan 2;128(1):120-124. doi: 10.1172/JCI92710. Epub 2017 Nov 20. J Clin Invest. 2018. PMID: 29202464 Free PMC article.

6

How the Ciliary Membrane Is Organized Inside-Out to Communicate Outside-In.

Garcia G 3rd, Raleigh DR, Reiter JF. Garcia G 3rd, et al. Among authors: reiter jf. Curr Biol. 2018 Apr 23;28(8):R421-R434. doi: 10.1016/j.cub.2018.03.010. Curr Biol. 2018. PMID: 29689227 Free PMC article. Review.

7

Cilia-Associated Oxysterols Activate Smoothened.

Raleigh DR, Sever N, Choksi PK, Sigg MA, Hines KM, Thompson BM, Elnatan D, Jaishankar P, Bisignano P, Garcia-Gonzalo FR, Krup AL, Eberl M, Byrne EFX, Siebold C, Wong SY, Renslo AR, Grabe M, McDonald JG, Xu L, Beachy PA, Reiter JF. Raleigh DR, et al. Among authors: reiter jf. Mol Cell. 2018 Oct 18;72(2):316-327.e5. doi: 10.1016/j.molcel.2018.08.034. Mol Cell. 2018. PMID: 30340023 Free PMC article.

8

Misactivation of Hedgehog signaling causes inherited and sporadic cancers.

Raleigh DR, Reiter JF. Raleigh DR, et al. Among authors: reiter jf. J Clin Invest. 2019 Feb 1;129(2):465-475. doi: 10.1172/JCI120850. Epub 2019 Feb 1. J Clin Invest. 2019. PMID: 30707108 Free PMC article. Review.

9

Sterol and oxysterol synthases near the ciliary base activate the Hedgehog pathway.

Findakly S, Daggubati V, Garcia G, LaStella SA, Choudhury A, Tran C, Li A, Tong P, Garcia JQ, Puri N, Reiter JF, Xu L, Raleigh DR. Findakly S, et al. Among authors: reiter jf. J Cell Biol. 2021 Jan 4;220(1):e202002026. doi: 10.1083/jcb.202002026. J Cell Biol. 2021. PMID: 33284321 Free PMC article.

10

Melanocortin 4 receptor signals at the neuronal primary cilium to control food intake and body weight.

Wang Y, Bernard A, Comblain F, Yue X, Paillart C, Zhang S, Reiter JF, Vaisse C. Wang Y, et al. Among authors: reiter jf. J Clin Invest. 2021 May 3;131(9):e142064. doi: 10.1172/JCI142064. J Clin Invest. 2021. PMID: 33938449 Free PMC article.

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