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The Human Milk Oligosaccharides 3-FL, Lacto-N-Neotetraose, and LDFT Attenuate Tumor Necrosis Factor-α Induced Inflammation in Fetal Intestinal Epithelial Cells In Vitro through Shedding or Interacting with Tumor Necrosis Factor Receptor 1.
Cheng L, Kong C, Wang W, Groeneveld A, Nauta A, Groves MR, Kiewiet MBG, de Vos P. Cheng L, et al. Among authors: groves mr. Mol Nutr Food Res. 2021 Apr;65(7):e2000425. doi: 10.1002/mnfr.202000425. Epub 2021 Mar 3. Mol Nutr Food Res. 2021. PMID: 33465830 Free PMC article.
Artificial Macrocycles as IL-17A/IL-17RA Antagonists.
Wang W, Groves MR, Dömling A. Wang W, et al. Among authors: groves mr. Medchemcomm. 2018 Jan 1;9(1):22-26. doi: 10.1039/C7MD00464H. Epub 2017 Oct 25. Medchemcomm. 2018. PMID: 29750108 Free PMC article.
Synthetic Peptides That Antagonize the Angiotensin-Converting Enzyme-2 (ACE-2) Interaction with SARS-CoV-2 Receptor Binding Spike Protein.
Sadremomtaz A, Al-Dahmani ZM, Ruiz-Moreno AJ, Monti A, Wang C, Azad T, Bell JC, Doti N, Velasco-Velázquez MA, de Jong D, de Jonge J, Smit J, Dömling A, van Goor H, Groves MR. Sadremomtaz A, et al. Among authors: groves mr. J Med Chem. 2022 Feb 24;65(4):2836-2847. doi: 10.1021/acs.jmedchem.1c00477. Epub 2021 Jul 30. J Med Chem. 2022. PMID: 34328726 Free PMC article.
DXS as a target for structure-based drug design.
Gierse RM, Redeem E, Diamanti E, Wrenger C, Groves MR, Hirsch AK. Gierse RM, et al. Among authors: groves mr. Future Med Chem. 2017 Jul;9(11):1277-1294. doi: 10.4155/fmc-2016-0239. Epub 2017 Jun 21. Future Med Chem. 2017. PMID: 28636418 Review.
Stapled Peptides Inhibitors: A New Window for Target Drug Discovery.
Ali AM, Atmaj J, Van Oosterwijk N, Groves MR, Dömling A. Ali AM, et al. Among authors: groves mr. Comput Struct Biotechnol J. 2019 Feb 19;17:263-281. doi: 10.1016/j.csbj.2019.01.012. eCollection 2019. Comput Struct Biotechnol J. 2019. PMID: 30867891 Free PMC article. Review.
Acoustic Droplet Ejection Enabled Automated Reaction Scouting.
Wang Y, Shaabani S, Ahmadianmoghaddam M, Gao L, Xu R, Kurpiewska K, Kalinowska-Tluscik J, Olechno J, Ellson R, Kossenjans M, Helan V, Groves M, Dömling A. Wang Y, et al. ACS Cent Sci. 2019 Mar 27;5(3):451-457. doi: 10.1021/acscentsci.8b00782. Epub 2019 Feb 27. ACS Cent Sci. 2019. PMID: 30937372 Free PMC article.
Rapid approach to complex boronic acids.
Neochoritis CG, Shaabani S, Ahmadianmoghaddam M, Zarganes-Tzitzikas T, Gao L, Novotná M, Mitríková T, Romero AR, Irianti MI, Xu R, Olechno J, Ellson R, Helan V, Kossenjans M, Groves MR, Dömling A. Neochoritis CG, et al. Among authors: groves mr. Sci Adv. 2019 Jul 5;5(7):eaaw4607. doi: 10.1126/sciadv.aaw4607. eCollection 2019 Jul. Sci Adv. 2019. PMID: 31281893 Free PMC article.
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