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The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair.
Shafi AA, McNair CM, McCann JJ, Alshalalfa M, Shostak A, Severson TM, Zhu Y, Bergman A, Gordon N, Mandigo AC, Chand SN, Gallagher P, Dylgjeri E, Laufer TS, Vasilevskaya IA, Schiewer MJ, Brunner M, Feng FY, Zwart W, Knudsen KE. Shafi AA, et al. Among authors: vasilevskaya ia. Nat Commun. 2021 Jan 15;12(1):401. doi: 10.1038/s41467-020-20513-5. Nat Commun. 2021. PMID: 33452241 Free PMC article.
Pleiotropic Impact of DNA-PK in Cancer and Implications for Therapeutic Strategies.
Dylgjeri E, McNair C, Goodwin JF, Raymon HK, McCue PA, Shafi AA, Leiby BE, de Leeuw R, Kothari V, McCann JJ, Mandigo AC, Chand SN, Schiewer MJ, Brand LJ, Vasilevskaya I, Gordon N, Laufer TS, Gomella LG, Lallas CD, Trabulsi EJ, Feng FY, Filvaroff EH, Hege K, Rathkopf D, Knudsen KE. Dylgjeri E, et al. Clin Cancer Res. 2019 Sep 15;25(18):5623-5637. doi: 10.1158/1078-0432.CCR-18-2207. Epub 2019 Jul 2. Clin Cancer Res. 2019. PMID: 31266833 Free PMC article.
USP22 Functions as an Oncogenic Driver in Prostate Cancer by Regulating Cell Proliferation and DNA Repair.
McCann JJ, Vasilevskaya IA, Poudel Neupane N, Shafi AA, McNair C, Dylgjeri E, Mandigo AC, Schiewer MJ, Schrecengost RS, Gallagher P, Stanek TJ, McMahon SB, Berman-Booty LD, Ostrander WF Jr, Knudsen KE. McCann JJ, et al. Among authors: vasilevskaya ia. Cancer Res. 2020 Feb 1;80(3):430-443. doi: 10.1158/0008-5472.CAN-19-1033. Epub 2019 Nov 18. Cancer Res. 2020. PMID: 31740444 Free PMC article.
RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease.
Mandigo AC, Yuan W, Xu K, Gallagher P, Pang A, Guan YF, Shafi AA, Thangavel C, Sheehan B, Bogdan D, Paschalis A, McCann JJ, Laufer TS, Gordon N, Vasilevskaya IA, Dylgjeri E, Chand SN, Schiewer MJ, Domingo-Domenech J, Den RB, Holst J, McCue PA, de Bono JS, McNair C, Knudsen KE. Mandigo AC, et al. Among authors: vasilevskaya ia. Cancer Discov. 2021 Sep;11(9):2334-2353. doi: 10.1158/2159-8290.CD-20-1114. Epub 2021 Apr 20. Cancer Discov. 2021. PMID: 33879449 Free PMC article.
Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer.
Mandigo AC, Shafi AA, McCann JJ, Yuan W, Laufer TS, Bogdan D, Gallagher L, Dylgjeri E, Semenova G, Vasilevskaya IA, Schiewer MJ, McNair CM, de Bono JS, Knudsen KE. Mandigo AC, et al. Among authors: vasilevskaya ia. Cancer Res. 2022 Jan 15;82(2):221-234. doi: 10.1158/0008-5472.CAN-21-1159. Epub 2021 Oct 8. Cancer Res. 2022. PMID: 34625422 Free PMC article.
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes.
McCann JJ, Vasilevskaya IA, McNair C, Gallagher P, Neupane NP, de Leeuw R, Shafi AA, Dylgjeri E, Mandigo AC, Schiewer MJ, Knudsen KE. McCann JJ, et al. Among authors: vasilevskaya ia. Oncogene. 2022 Jan;41(3):444-458. doi: 10.1038/s41388-021-01903-5. Epub 2021 Nov 12. Oncogene. 2022. PMID: 34773073 Free PMC article.
A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer.
Dylgjeri E, Kothari V, Shafi AA, Semenova G, Gallagher PT, Guan YF, Pang A, Goodwin JF, Irani S, McCann JJ, Mandigo AC, Chand S, McNair CM, Vasilevskaya I, Schiewer MJ, Lallas CD, McCue PA, Gomella LG, Seifert EL, Carroll JS, Butler LM, Holst J, Kelly WK, Knudsen KE. Dylgjeri E, et al. Clin Cancer Res. 2022 Apr 1;28(7):1446-1459. doi: 10.1158/1078-0432.CCR-21-1846. Clin Cancer Res. 2022. PMID: 35078861 Free PMC article.
27-hydroxycholesterol and DNA damage repair: implication in prostate cancer.
Galvan GC, Friedrich NA, Das S, Daniels JP, Pollan S, Dambal S, Suzuki R, Sanders SE, You S, Tanaka H, Lee YJ, Yuan W, de Bono JS, Vasilevskaya I, Knudsen KE, Freeman MR, Freedland SJ. Galvan GC, et al. Front Oncol. 2023 Dec 21;13:1251297. doi: 10.3389/fonc.2023.1251297. eCollection 2023. Front Oncol. 2023. PMID: 38188290 Free PMC article.
25 results