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Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo.
Ogasawara D, Ichu TA, Vartabedian VF, Benthuysen J, Jing H, Reed A, Ulanovskaya OA, Hulce JJ, Roberts A, Brown S, Rosen H, Teijaro JR, Cravatt BF. Ogasawara D, et al. Among authors: reed a. Nat Chem Biol. 2018 Dec;14(12):1099-1108. doi: 10.1038/s41589-018-0155-8. Epub 2018 Nov 12. Nat Chem Biol. 2018. PMID: 30420694 Free PMC article.
Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling.
Bi J, Ichu TA, Zanca C, Yang H, Zhang W, Gu Y, Chowdhry S, Reed A, Ikegami S, Turner KM, Zhang W, Villa GR, Wu S, Quehenberger O, Yong WH, Kornblum HI, Rich JN, Cloughesy TF, Cavenee WK, Furnari FB, Cravatt BF, Mischel PS. Bi J, et al. Among authors: reed a. Cell Metab. 2019 Sep 3;30(3):525-538.e8. doi: 10.1016/j.cmet.2019.06.014. Epub 2019 Jul 11. Cell Metab. 2019. PMID: 31303424 Free PMC article.
ABHD12 and LPCAT3 Interplay Regulates a Lyso-phosphatidylserine-C20:4 Phosphatidylserine Lipid Network Implicated in Neurological Disease.
Ichu TA, Reed A, Ogasawara D, Ulanovskaya O, Roberts A, Aguirre CA, Bar-Peled L, Gao J, Germain J, Barbas S, Masuda K, Conti B, Tontonoz P, Cravatt BF. Ichu TA, et al. Among authors: reed a. Biochemistry. 2020 May 19;59(19):1793-1799. doi: 10.1021/acs.biochem.0c00292. Epub 2020 May 4. Biochemistry. 2020. PMID: 32364701 Free PMC article.
Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Bi J, Khan A, Tang J, Armando AM, Wu S, Zhang W, Gimple RC, Reed A, Jing H, Koga T, Wong IT, Gu Y, Miki S, Yang H, Prager B, Curtis EJ, Wainwright DA, Furnari FB, Rich JN, Cloughesy TF, Kornblum HI, Quehenberger O, Rzhetsky A, Cravatt BF, Mischel PS. Bi J, et al. Among authors: reed a. Cell Rep. 2021 Nov 2;37(5):109957. doi: 10.1016/j.celrep.2021.109957. Cell Rep. 2021. PMID: 34731610 Free PMC article.
Aspirin modulates generation of procoagulant phospholipids in cardiovascular disease, by regulating LPCAT3.
Protty MB, Tyrrell VJ, Hajeyah AA, Morgan B, Costa D, Li Y, Choudhury A, Mitra R, Bosanquet D, Reed A, Denisenko IK, Nagata K, Shindou H, Cravatt BF, Poole AW, Shimizu T, Yousef Z, Collins PW, O'Donnell VB. Protty MB, et al. Among authors: reed a. J Lipid Res. 2024 Dec 12:100727. doi: 10.1016/j.jlr.2024.100727. Online ahead of print. J Lipid Res. 2024. PMID: 39674322 Free article.
1,395 results