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Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces shedding of SARS-CoV-2 D614G in rhesus macaques.
van Doremalen N, Purushotham JN, Schulz JE, Holbrook MG, Bushmaker T, Carmody A, Port JR, Yinda CK, Okumura A, Saturday G, Amanat F, Krammer F, Hanley PW, Smith BJ, Lovaglio J, Anzick SL, Barbian K, Martens C, Gilbert S, Lambe T, Munster VJ. van Doremalen N, et al. Among authors: martens c. bioRxiv [Preprint]. 2021 Jan 11:2021.01.09.426058. doi: 10.1101/2021.01.09.426058. bioRxiv. 2021. Update in: Sci Transl Med. 2021 Aug 18;13(607):eabh0755. doi: 10.1126/scitranslmed.abh0755 PMID: 33447831 Free PMC article. Updated. Preprint.
Vaccine Protection against Multidrug-Resistant Klebsiella pneumoniae in a Nonhuman Primate Model of Severe Lower Respiratory Tract Infection.
Malachowa N, Kobayashi SD, Porter AR, Freedman B, Hanley PW, Lovaglio J, Saturday GA, Gardner DJ, Scott DP, Griffin A, Cordova K, Long D, Rosenke R, Sturdevant DE, Bruno D, Martens C, Kreiswirth BN, DeLeo FR. Malachowa N, et al. Among authors: martens c. mBio. 2019 Dec 17;10(6):e02994-19. doi: 10.1128/mBio.02994-19. mBio. 2019. PMID: 31848292 Free PMC article.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Williamson BN, Feldmann F, Schwarz B, Meade-White K, Porter DP, Schulz J, van Doremalen N, Leighton I, Kwe Yinda C, Pérez-Pérez L, Okumura A, Lovaglio J, Hanley PW, Saturday G, Bosio CM, Anzick S, Barbian K, Cihlar T, Martens C, Scott DP, Munster VJ, de Wit E. Williamson BN, et al. Among authors: martens c. bioRxiv [Preprint]. 2020 Apr 22:2020.04.15.043166. doi: 10.1101/2020.04.15.043166. bioRxiv. 2020. Update in: Nature. 2020 Sep;585(7824):273-276. doi: 10.1038/s41586-020-2423-5 PMID: 32511319 Free PMC article. Updated. Preprint.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Williamson BN, Feldmann F, Schwarz B, Meade-White K, Porter DP, Schulz J, van Doremalen N, Leighton I, Yinda CK, Pérez-Pérez L, Okumura A, Lovaglio J, Hanley PW, Saturday G, Bosio CM, Anzick S, Barbian K, Cihlar T, Martens C, Scott DP, Munster VJ, de Wit E. Williamson BN, et al. Among authors: martens c. Nature. 2020 Sep;585(7824):273-276. doi: 10.1038/s41586-020-2423-5. Epub 2020 Jun 9. Nature. 2020. PMID: 32516797 Free PMC article.
SARS-CoV-2 infection dynamics in lungs of African green monkeys.
Speranza E, Williamson BN, Feldmann F, Sturdevant GL, Pérez-Pérez L, Mead-White K, Smith BJ, Lovaglio J, Martens C, Munster VJ, Okumura A, Shaia C, Feldmann H, Best SM, de Wit E. Speranza E, et al. Among authors: martens c. bioRxiv [Preprint]. 2020 Aug 20:2020.08.20.258087. doi: 10.1101/2020.08.20.258087. bioRxiv. 2020. Update in: Sci Transl Med. 2021 Jan 27;13(578):eabe8146. doi: 10.1126/scitranslmed.abe8146 PMID: 32839775 Free PMC article. Updated. Preprint.
Single-cell RNA sequencing reveals SARS-CoV-2 infection dynamics in lungs of African green monkeys.
Speranza E, Williamson BN, Feldmann F, Sturdevant GL, Pérez-Pérez L, Meade-White K, Smith BJ, Lovaglio J, Martens C, Munster VJ, Okumura A, Shaia C, Feldmann H, Best SM, de Wit E. Speranza E, et al. Among authors: martens c. Sci Transl Med. 2021 Jan 27;13(578):eabe8146. doi: 10.1126/scitranslmed.abe8146. Epub 2021 Jan 11. Sci Transl Med. 2021. PMID: 33431511 Free PMC article.
ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7.
Fischer RJ, van Doremalen N, Adney DR, Yinda CK, Port JR, Holbrook MG, Schulz JE, Williamson BN, Thomas T, Barbian K, Anzick SL, Ricklefs S, Smith BJ, Long D, Martens C, Saturday G, de Wit E, Gilbert SC, Lambe T, Munster VJ. Fischer RJ, et al. Among authors: martens c. bioRxiv [Preprint]. 2021 Jun 30:2021.03.11.435000. doi: 10.1101/2021.03.11.435000. bioRxiv. 2021. Update in: Nat Commun. 2021 Oct 7;12(1):5868. doi: 10.1038/s41467-021-26178-y PMID: 33758847 Free PMC article. Updated. Preprint.
Orally delivered MK-4482 inhibits SARS-CoV-2 replication in the Syrian hamster model.
Rosenke K, Hansen F, Schwarz B, Feldmann F, Haddock E, Rosenke R, Barbian K, Meade-White K, Okumura A, Leventhal S, Hawman DW, Ricotta E, Bosio CM, Martens C, Saturday G, Feldmann H, Jarvis MA. Rosenke K, et al. Among authors: martens c. Nat Commun. 2021 Apr 16;12(1):2295. doi: 10.1038/s41467-021-22580-8. Nat Commun. 2021. PMID: 33863887 Free PMC article.
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models.
van Doremalen N, Purushotham JN, Schulz JE, Holbrook MG, Bushmaker T, Carmody A, Port JR, Yinda CK, Okumura A, Saturday G, Amanat F, Krammer F, Hanley PW, Smith BJ, Lovaglio J, Anzick SL, Barbian K, Martens C, Gilbert SC, Lambe T, Munster VJ. van Doremalen N, et al. Among authors: martens c. Sci Transl Med. 2021 Aug 18;13(607):eabh0755. doi: 10.1126/scitranslmed.abh0755. Epub 2021 Jul 27. Sci Transl Med. 2021. PMID: 34315826 Free PMC article.
386 results