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An Autochthonous Mouse Model of Myd88- and BCL2-Driven Diffuse Large B-cell Lymphoma Reveals Actionable Molecular Vulnerabilities.
Flümann R, Rehkämper T, Nieper P, Pfeiffer P, Holzem A, Klein S, Bhatia S, Kochanek M, Kisis I, Pelzer BW, Ahlert H, Hauer J, da Palma Guerreiro A, Ryan JA, Reimann M, Riabinska A, Wiederstein J, Krüger M, Deckert M, Altmüller J, Klatt AR, Frenzel LP, Pasqualucci L, Béguelin W, Melnick AM, Sander S, Montesinos-Rongen M, Brunn A, Lohneis P, Büttner R, Kashkar H, Borkhardt A, Letai A, Persigehl T, Peifer M, Schmitt CA, Reinhardt HC, Knittel G. Flümann R, et al. Among authors: pasqualucci l. Blood Cancer Discov. 2021 Jan;2(1):70-91. doi: 10.1158/2643-3230.BCD-19-0059. Blood Cancer Discov. 2021. PMID: 33447829 Free PMC article.
Expression of the AID protein in normal and neoplastic B cells.
Pasqualucci L, Guglielmino R, Houldsworth J, Mohr J, Aoufouchi S, Polakiewicz R, Chaganti RS, Dalla-Favera R. Pasqualucci L, et al. Blood. 2004 Nov 15;104(10):3318-25. doi: 10.1182/blood-2004-04-1558. Epub 2004 Aug 10. Blood. 2004. PMID: 15304391 Free article.
Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma.
Pasqualucci L, Compagno M, Houldsworth J, Monti S, Grunn A, Nandula SV, Aster JC, Murty VV, Shipp MA, Dalla-Favera R. Pasqualucci L, et al. J Exp Med. 2006 Feb 20;203(2):311-7. doi: 10.1084/jem.20052204. J Exp Med. 2006. PMID: 16492805 Free PMC article.
Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.
Compagno M, Lim WK, Grunn A, Nandula SV, Brahmachary M, Shen Q, Bertoni F, Ponzoni M, Scandurra M, Califano A, Bhagat G, Chadburn A, Dalla-Favera R, Pasqualucci L. Compagno M, et al. Among authors: pasqualucci l. Nature. 2009 Jun 4;459(7247):717-21. doi: 10.1038/nature07968. Epub 2009 May 3. Nature. 2009. PMID: 19412164 Free PMC article.
BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.
Saito M, Novak U, Piovan E, Basso K, Sumazin P, Schneider C, Crespo M, Shen Q, Bhagat G, Califano A, Chadburn A, Pasqualucci L, Dalla-Favera R. Saito M, et al. Among authors: pasqualucci l. Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11294-9. doi: 10.1073/pnas.0903854106. Epub 2009 Jun 23. Proc Natl Acad Sci U S A. 2009. PMID: 19549844 Free PMC article.
124 results