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Page 1
Risk of Early-Onset Depression Associated With Polygenic Liability, Parental Psychiatric History, and Socioeconomic Status.
Agerbo E, Trabjerg BB, Børglum AD, Schork AJ, Vilhjálmsson BJ, Pedersen CB, Hakulinen C, Albiñana C, Hougaard DM, Grove J, McGrath JJ, Bybjerg-Grauholm J, Mors O, Plana-Ripoll O, Werge T, Wray NR, Mortensen PB, Musliner KL. Agerbo E, et al. Among authors: schork aj. JAMA Psychiatry. 2021 Apr 1;78(4):387-397. doi: 10.1001/jamapsychiatry.2020.4172. JAMA Psychiatry. 2021. PMID: 33439215 Free PMC article.
All SNPs are not created equal: genome-wide association studies reveal a consistent pattern of enrichment among functionally annotated SNPs.
Schork AJ, Thompson WK, Pham P, Torkamani A, Roddey JC, Sullivan PF, Kelsoe JR, O'Donovan MC, Furberg H; Tobacco and Genetics Consortium; Bipolar Disorder Psychiatric Genomics Consortium; Schizophrenia Psychiatric Genomics Consortium; Schork NJ, Andreassen OA, Dale AM. Schork AJ, et al. Among authors: schork nj. PLoS Genet. 2013 Apr;9(4):e1003449. doi: 10.1371/journal.pgen.1003449. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637621 Free PMC article.
Improved detection of common variants associated with schizophrenia and bipolar disorder using pleiotropy-informed conditional false discovery rate.
Andreassen OA, Thompson WK, Schork AJ, Ripke S, Mattingsdal M, Kelsoe JR, Kendler KS, O'Donovan MC, Rujescu D, Werge T, Sklar P; Psychiatric Genomics Consortium (PGC); Bipolar Disorder and Schizophrenia Working Groups; Roddey JC, Chen CH, McEvoy L, Desikan RS, Djurovic S, Dale AM. Andreassen OA, et al. Among authors: schork aj. PLoS Genet. 2013 Apr;9(4):e1003455. doi: 10.1371/journal.pgen.1003455. Epub 2013 Apr 25. PLoS Genet. 2013. PMID: 23637625 Free PMC article.
Genetic Markers of Human Evolution Are Enriched in Schizophrenia.
Srinivasan S, Bettella F, Mattingsdal M, Wang Y, Witoelar A, Schork AJ, Thompson WK, Zuber V; Schizophrenia Working Group of the Psychiatric Genomics Consortium, The International Headache Genetics Consortium; Winsvold BS, Zwart JA, Collier DA, Desikan RS, Melle I, Werge T, Dale AM, Djurovic S, Andreassen OA. Srinivasan S, et al. Among authors: schork aj. Biol Psychiatry. 2016 Aug 15;80(4):284-292. doi: 10.1016/j.biopsych.2015.10.009. Epub 2015 Oct 21. Biol Psychiatry. 2016. PMID: 26681495 Free PMC article.
An Empirical Bayes Mixture Model for Effect Size Distributions in Genome-Wide Association Studies.
Thompson WK, Wang Y, Schork AJ, Witoelar A, Zuber V, Xu S, Werge T, Holland D; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Andreassen OA, Dale AM. Thompson WK, et al. Among authors: schork aj. PLoS Genet. 2015 Dec 29;11(12):e1005717. doi: 10.1371/journal.pgen.1005717. eCollection 2015 Dec. PLoS Genet. 2015. PMID: 26714184 Free PMC article.
Leveraging Genomic Annotations and Pleiotropic Enrichment for Improved Replication Rates in Schizophrenia GWAS.
Wang Y, Thompson WK, Schork AJ, Holland D, Chen CH, Bettella F, Desikan RS, Li W, Witoelar A, Zuber V, Devor A; Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium; Enhancing Neuro Imaging Genetics through Meta Analysis Consortium; Nöthen MM, Rietschel M, Chen Q, Werge T, Cichon S, Weinberger DR, Djurovic S, O'Donovan M, Visscher PM, Andreassen OA, Dale AM. Wang Y, et al. Among authors: schork aj. PLoS Genet. 2016 Jan 25;12(1):e1005803. doi: 10.1371/journal.pgen.1005803. eCollection 2016 Jan. PLoS Genet. 2016. PMID: 26808560 Free PMC article.
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept.
Franke B, Stein JL, Ripke S, Anttila V, Hibar DP, van Hulzen KJE, Arias-Vasquez A, Smoller JW, Nichols TE, Neale MC, McIntosh AM, Lee P, McMahon FJ, Meyer-Lindenberg A, Mattheisen M, Andreassen OA, Gruber O, Sachdev PS, Roiz-Santiañez R, Saykin AJ, Ehrlich S, Mather KA, Turner JA, Schwarz E, Thalamuthu A, Shugart YY, Ho YY, Martin NG, Wright MJ; Schizophrenia Working Group of the Psychiatric Genomics Consortium; ENIGMA Consortium; O'Donovan MC, Thompson PM, Neale BM, Medland SE, Sullivan PF. Franke B, et al. Nat Neurosci. 2016 Mar;19(3):420-431. doi: 10.1038/nn.4228. Epub 2016 Feb 1. Nat Neurosci. 2016. PMID: 26854805 Free PMC article.
Estimating Effect Sizes and Expected Replication Probabilities from GWAS Summary Statistics.
Holland D, Wang Y, Thompson WK, Schork A, Chen CH, Lo MT, Witoelar A; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Enhancing Neuro Imaging Genetics through Meta Analysis Consortium; Werge T, O'Donovan M, Andreassen OA, Dale AM. Holland D, et al. Front Genet. 2016 Feb 16;7:15. doi: 10.3389/fgene.2016.00015. eCollection 2016. Front Genet. 2016. PMID: 26909100 Free PMC article.
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment.
Shadrin AA, Smeland OB, Zayats T, Schork AJ, Frei O, Bettella F, Witoelar A, Li W, Eriksen JA, Krull F, Djurovic S, Faraone SV, Reichborn-Kjennerud T, Thompson WK, Johansson S, Haavik J, Dale AM, Wang Y, Andreassen OA. Shadrin AA, et al. Among authors: schork aj. J Am Acad Child Adolesc Psychiatry. 2018 Feb;57(2):86-95. doi: 10.1016/j.jaac.2017.11.013. Epub 2017 Nov 26. J Am Acad Child Adolesc Psychiatry. 2018. PMID: 29413154 Free PMC article.
Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap.
Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP; CommonMind Consortium; PsychENCODE Consortium; iPSYCH-BROAD Working Group; Horvath S, Geschwind DH. Gandal MJ, et al. Among authors: schork aj. Science. 2018 Feb 9;359(6376):693-697. doi: 10.1126/science.aad6469. Science. 2018. PMID: 29439242 Free PMC article.
161 results