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A multi-centre, open label, randomised, parallel-group, superiority Trial to compare the efficacy of URsodeoxycholic acid with RIFampicin in the management of women with severe early onset Intrahepatic Cholestasis of pregnancy: the TURRIFIC randomised trial.
Hague WM, Callaway L, Chambers J, Chappell L, Coat S, de Haan-Jebbink J, Dekker M, Dixon P, Dodd J, Fuller M, Gordijn S, Graham D, Heikinheimo O, Hennessy A, Kaaja R, Khong TY, Lampio L, Louise J, Makris A, Markus C, Marschall HU, Middleton P, Mol BW, Morris J, Newnham JP, Ovadia C, Peek M, Shand A, Stark M, Thornton J, Timonen S, Walker S, Warrilow D, Williamson C. Hague WM, et al. Among authors: chappell l. BMC Pregnancy Childbirth. 2021 Jan 12;21(1):51. doi: 10.1186/s12884-020-03481-y. BMC Pregnancy Childbirth. 2021. PMID: 33435904 Free PMC article.
Fetal cardiac dysfunction in intrahepatic cholestasis of pregnancy is associated with elevated serum bile acid concentrations.
Vasavan T, Deepak S, Jayawardane IA, Lucchini M, Martin C, Geenes V, Yang J, Lövgren-Sandblom A, Seed PT, Chambers J, Stone S, Kurlak L, Dixon PH, Marschall HU, Gorelik J, Chappell L, Loughna P, Thornton J, Pipkin FB, Hayes-Gill B, Fifer WP, Williamson C. Vasavan T, et al. Among authors: chappell l. J Hepatol. 2021 May;74(5):1087-1096. doi: 10.1016/j.jhep.2020.11.038. Epub 2020 Dec 1. J Hepatol. 2021. PMID: 33276032 Free PMC article.
Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum.
Abu-Hayyeh S, Ovadia C, Lieu T, Jensen DD, Chambers J, Dixon PH, Lövgren-Sandblom A, Bolier R, Tolenaars D, Kremer AE, Syngelaki A, Noori M, Williams D, Marin JJ, Monte MJ, Nicolaides KH, Beuers U, Oude-Elferink R, Seed PT, Chappell L, Marschall HU, Bunnett NW, Williamson C. Abu-Hayyeh S, et al. Among authors: chappell l. Hepatology. 2016 Apr;63(4):1287-98. doi: 10.1002/hep.28265. Epub 2015 Dec 28. Hepatology. 2016. PMID: 26426865 Free PMC article.
PREPARE: protocol for a stepped wedge trial to evaluate whether a risk stratification model can reduce preterm deliveries among women with suspected or confirmed preterm pre-eclampsia.
Dias MAB, De Oliveira L, Jeyabalan A, Payne B, Redman CW, Magee L, Poston L, Chappell L, Seed P, von Dadelszen P, Roberts JM; PREPARE Research Group. Dias MAB, et al. Among authors: chappell l. BMC Pregnancy Childbirth. 2019 Oct 7;19(1):343. doi: 10.1186/s12884-019-2445-x. BMC Pregnancy Childbirth. 2019. PMID: 31590640 Free PMC article.
457 results