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MHC multimer-guided and cell culture-independent isolation of functional T cell receptors from single cells facilitates TCR identification for immunotherapy.
Dössinger G, Bunse M, Bet J, Albrecht J, Paszkiewicz PJ, Weißbrich B, Schiedewitz I, Henkel L, Schiemann M, Neuenhahn M, Uckert W, Busch DH. Dössinger G, et al. Among authors: uckert w. PLoS One. 2013 Apr 26;8(4):e61384. doi: 10.1371/journal.pone.0061384. Print 2013. PLoS One. 2013. PMID: 23637823 Free PMC article.
Domain-swapped T cell receptors improve the safety of TCR gene therapy.
Bethune MT, Gee MH, Bunse M, Lee MS, Gschweng EH, Pagadala MS, Zhou J, Cheng D, Heath JR, Kohn DB, Kuhns MS, Uckert W, Baltimore D. Bethune MT, et al. Among authors: uckert w. Elife. 2016 Nov 8;5:e19095. doi: 10.7554/eLife.19095. Elife. 2016. PMID: 27823582 Free PMC article.
TCR-ligand koff rate correlates with the protective capacity of antigen-specific CD8+ T cells for adoptive transfer.
Nauerth M, Weißbrich B, Knall R, Franz T, Dössinger G, Bet J, Paszkiewicz PJ, Pfeifer L, Bunse M, Uckert W, Holtappels R, Gillert-Marien D, Neuenhahn M, Krackhardt A, Reddehase MJ, Riddell SR, Busch DH. Nauerth M, et al. Among authors: uckert w. Sci Transl Med. 2013 Jul 3;5(192):192ra87. doi: 10.1126/scitranslmed.3005958. Sci Transl Med. 2013. PMID: 23825303 Free PMC article.
T cells expressing a chimeric antigen receptor that binds hepatitis B virus envelope proteins control virus replication in mice.
Krebs K, Böttinger N, Huang LR, Chmielewski M, Arzberger S, Gasteiger G, Jäger C, Schmitt E, Bohne F, Aichler M, Uckert W, Abken H, Heikenwalder M, Knolle P, Protzer U. Krebs K, et al. Among authors: uckert w. Gastroenterology. 2013 Aug;145(2):456-65. doi: 10.1053/j.gastro.2013.04.047. Epub 2013 Apr 30. Gastroenterology. 2013. PMID: 23639914 Free article.
130 results