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A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de Los Santos M, Rivalan M, David FS, Stumpf A, Pitsch J, Tsortouktzidis D, Velasquez LM, Voigt A, Schilling K, Mattei D, Long M, Vogt G, Knaus A, Fischer-Zirnsak B, Wittler L, Timmermann B, Robinson PN, Horn D, Mundlos S, Kornak U, Becker AJ, Schmitz D, Winter Y, Krawitz PM. Rodríguez de Los Santos M, et al. Among authors: stumpf a. Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2014481118. doi: 10.1073/pnas.2014481118. Proc Natl Acad Sci U S A. 2021. PMID: 33402532 Free PMC article.
RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses.
Grauel MK, Maglione M, Reddy-Alla S, Willmes CG, Brockmann MM, Trimbuch T, Rosenmund T, Pangalos M, Vardar G, Stumpf A, Walter AM, Rost BR, Eickholt BJ, Haucke V, Schmitz D, Sigrist SJ, Rosenmund C. Grauel MK, et al. Among authors: stumpf a. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):11615-11620. doi: 10.1073/pnas.1605256113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671655 Free PMC article.
SORCS1 and SORCS3 control energy balance and orexigenic peptide production.
Subkhangulova A, Malik AR, Hermey G, Popp O, Dittmar G, Rathjen T, Poy MN, Stumpf A, Beed PS, Schmitz D, Breiderhoff T, Willnow TE. Subkhangulova A, et al. Among authors: stumpf a. EMBO Rep. 2018 Apr;19(4):e44810. doi: 10.15252/embr.201744810. Epub 2018 Feb 12. EMBO Rep. 2018. PMID: 29440124 Free PMC article.
Species-specific differences in synaptic transmission and plasticity.
Beed P, Ray S, Velasquez LM, Stumpf A, Parthier D, Swaminathan A, Nitzan N, Breustedt J, Las L, Brecht M, Schmitz D. Beed P, et al. Among authors: stumpf a. Sci Rep. 2020 Oct 6;10(1):16557. doi: 10.1038/s41598-020-73547-6. Sci Rep. 2020. PMID: 33024184 Free PMC article.
112 results