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A CRISPR-Cas9-engineered mouse model for GPI-anchor deficiency mirrors human phenotypes and exhibits hippocampal synaptic dysfunctions.
Rodríguez de Los Santos M, Rivalan M, David FS, Stumpf A, Pitsch J, Tsortouktzidis D, Velasquez LM, Voigt A, Schilling K, Mattei D, Long M, Vogt G, Knaus A, Fischer-Zirnsak B, Wittler L, Timmermann B, Robinson PN, Horn D, Mundlos S, Kornak U, Becker AJ, Schmitz D, Winter Y, Krawitz PM. Rodríguez de Los Santos M, et al. Among authors: mattei d. Proc Natl Acad Sci U S A. 2021 Jan 12;118(2):e2014481118. doi: 10.1073/pnas.2014481118. Proc Natl Acad Sci U S A. 2021. PMID: 33402532 Free PMC article.
Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment.
Mattei D, Ivanov A, Ferrai C, Jordan P, Guneykaya D, Buonfiglioli A, Schaafsma W, Przanowski P, Deuther-Conrad W, Brust P, Hesse S, Patt M, Sabri O, Ross TL, Eggen BJL, Boddeke EWGM, Kaminska B, Beule D, Pombo A, Kettenmann H, Wolf SA. Mattei D, et al. Transl Psychiatry. 2017 May 9;7(5):e1120. doi: 10.1038/tp.2017.80. Transl Psychiatry. 2017. PMID: 28485733 Free PMC article.
Reduction of cortical parvalbumin-expressing GABAergic interneurons in a rodent hyperoxia model of preterm birth brain injury with deficits in social behavior and cognition.
Scheuer T, dem Brinke EA, Grosser S, Wolf SA, Mattei D, Sharkovska Y, Barthel PC, Endesfelder S, Friedrich V, Bührer C, Vida I, Schmitz T. Scheuer T, et al. Among authors: mattei d. Development. 2021 Oct 15;148(20):dev198390. doi: 10.1242/dev.198390. Epub 2021 Oct 14. Development. 2021. PMID: 34557899
Adolescence is a sensitive period for prefrontal microglia to act on cognitive development.
Schalbetter SM, von Arx AS, Cruz-Ochoa N, Dawson K, Ivanov A, Mueller FS, Lin HY, Amport R, Mildenberger W, Mattei D, Beule D, Földy C, Greter M, Notter T, Meyer U. Schalbetter SM, et al. Among authors: mattei d. Sci Adv. 2022 Mar 4;8(9):eabi6672. doi: 10.1126/sciadv.abi6672. Epub 2022 Mar 2. Sci Adv. 2022. PMID: 35235358 Free PMC article.
159 results