Chen L - Search Results

1

Correction: Synthesis and biological evaluation of hybrids from farnesylthiosalicylic acid and hydroxylcinnamic acid with dual inhibitory activities of Ras-related signaling and phosphorylated NF-κB.

Ling Y, Wang Z, Wang X, Zhao Y, Zhang W, Wang X, Chen L, Huang Z, Zhang Y. Ling Y, et al. Among authors: chen l. Org Biomol Chem. 2021 Jan 21;19(2):486. doi: 10.1039/d0ob90173c. Org Biomol Chem. 2021. PMID: 33393555

2

Design, synthesis and cytotoxic evaluation of nitric oxide-releasing derivatives of isosteviol.

Liu Y, Wang T, Ling Y, Bao N, Shi W, Chen L, Sun J. Liu Y, et al. Among authors: chen l. Chem Biol Drug Des. 2017 Sep;90(3):473-477. doi: 10.1111/cbdd.12956. Epub 2017 Feb 22. Chem Biol Drug Des. 2017. PMID: 28122177

3

Design, Synthesis, and Biological Evaluation of Esculetin-Furoxan-DEAC Ternary Hybrids for Anti-Triple Negative Breast Cancer.

Wen M, Sun J, Yang M, Zhang X, Wang Y, Zhou W, Shi Y, Huang Y, Li N, Chen L. Wen M, et al. Among authors: chen l. J Med Chem. 2023 Sep 14;66(17):12446-12458. doi: 10.1021/acs.jmedchem.3c00954. Epub 2023 Aug 21. J Med Chem. 2023. PMID: 37602711

4

Design, synthesis and cytotoxic activities of scopoletin-isoxazole and scopoletin-pyrazole hybrids.

Shi W, Hu J, Bao N, Li D, Chen L, Sun J. Shi W, et al. Among authors: chen l. Bioorg Med Chem Lett. 2017 Jan 15;27(2):147-151. doi: 10.1016/j.bmcl.2016.11.089. Epub 2016 Dec 1. Bioorg Med Chem Lett. 2017. PMID: 27956344

5

Discovery of Novel Anti-Breast-Cancer Inhibitors by Synergistically Antagonizing Microtubule Polymerization and Aryl Hydrocarbon Receptor Expression.

Wang K, Zhong H, Li N, Yu N, Wang Y, Chen L, Sun J. Wang K, et al. Among authors: chen l. J Med Chem. 2021 Sep 9;64(17):12964-12977. doi: 10.1021/acs.jmedchem.1c01099. Epub 2021 Aug 24. J Med Chem. 2021. PMID: 34428056

6

Development of MAO-A and 5-HT_2AR Dual Inhibitors with Improved Antidepressant Activity.

Sun X, Li N, Zhong P, Chen L, Sun J. Sun X, et al. Among authors: chen l. J Med Chem. 2022 Oct 13;65(19):13385-13400. doi: 10.1021/acs.jmedchem.2c01271. Epub 2022 Sep 29. J Med Chem. 2022. PMID: 36173886

7

Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.

Qi M, Zhong H, Cheng Z, Chen S, Xiao H, Shang J, Chen L, Sun J. Qi M, et al. Among authors: chen l, chen s. J Med Chem. 2023 Jul 13;66(13):9184-9200. doi: 10.1021/acs.jmedchem.3c00822. Epub 2023 Jun 30. J Med Chem. 2023. PMID: 37386884

8

Development of Nitric Oxide Releasing Oxoisoaporphines with Antidepressant Activities by Simultaneously Regulating MAO-A and SERT.

Zhong P, Mao X, Li N, Chen L, Sun J. Zhong P, et al. Among authors: chen l. J Med Chem. 2024 Sep 12;67(17):15509-15520. doi: 10.1021/acs.jmedchem.4c01161. Epub 2024 Aug 27. J Med Chem. 2024. PMID: 39189331

9

Design, synthesis and biological evaluation of multifunctional tacrine-curcumin hybrids as new cholinesterase inhibitors with metal ions-chelating and neuroprotective property.

Liu Z, Fang L, Zhang H, Gou S, Chen L. Liu Z, et al. Among authors: chen l. Bioorg Med Chem. 2017 Apr 15;25(8):2387-2398. doi: 10.1016/j.bmc.2017.02.049. Epub 2017 Mar 6. Bioorg Med Chem. 2017. PMID: 28302511

10

Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity.

Li N, Xu M, Wang B, Shi Z, Zhao Z, Tang Y, Wang X, Sun J, Chen L. Li N, et al. Among authors: chen l. J Med Chem. 2019 Dec 12;62(23):10798-10815. doi: 10.1021/acs.jmedchem.9b01290. Epub 2019 Dec 3. J Med Chem. 2019. PMID: 31725288

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