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Page 1
Generation of a Genetically Modified Chimeric Plasmodium falciparum Parasite Expressing Plasmodium vivax Circumsporozoite Protein for Malaria Vaccine Development.
Miyazaki Y, Marin-Mogollon C, Imai T, Mendes AM, van der Laak R, Sturm A, Geurten FJA, Miyazaki S, Chevalley-Maurel S, Ramesar J, Kolli SK, Kroeze H, van Schuijlenburg R, Salman AM, Wilder BK, Reyes-Sandoval A, Dechering KJ, Prudêncio M, Janse CJ, Khan SM, Franke-Fayard B. Miyazaki Y, et al. Among authors: geurten fja. Front Cell Infect Microbiol. 2020 Dec 17;10:591046. doi: 10.3389/fcimb.2020.591046. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33392104 Free PMC article.
Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters.
Miyazaki S, Yang ASP, Geurten FJA, Marin-Mogollon C, Miyazaki Y, Imai T, Kolli SK, Ramesar J, Chevalley-Maurel S, Salman AM, van Gemert GA, van Waardenburg YM, Franke-Fayard B, Hill AVS, Sauerwein RW, Janse CJ, Khan SM. Miyazaki S, et al. Among authors: geurten fja. Front Cell Infect Microbiol. 2020 Jun 10;10:270. doi: 10.3389/fcimb.2020.00270. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32587831 Free PMC article.
Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification.
Kolli SK, Molina-Cruz A, Araki T, Geurten FJA, Ramesar J, Chevalley-Maurel S, Kroeze HJ, Bezemer S, de Korne C, Withers R, Raytselis N, El Hebieshy AF, Kim RQ, Child MA, Kakuta S, Hisaeda H, Kobayashi H, Annoura T, Hensbergen PJ, Franke-Fayard BM, Barillas-Mury C, Scheeren FA, Janse CJ. Kolli SK, et al. Among authors: geurten fja. Proc Natl Acad Sci U S A. 2022 Aug 30;119(35):e2209729119. doi: 10.1073/pnas.2209729119. Epub 2022 Aug 22. Proc Natl Acad Sci U S A. 2022. PMID: 35994647 Free PMC article.
Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver.
Franke-Fayard B, Marin-Mogollon C, Geurten FJA, Chevalley-Maurel S, Ramesar J, Kroeze H, Baalbergen E, Wessels E, Baron L, Soulard V, Martinson T, Aleshnick M, Huijs ATG, Subudhi AK, Miyazaki Y, Othman AS, Kolli SK, Lamers OAC, Roques M, Stanway RR, Murphy SC, Foquet L, Moita D, Mendes AM, Prudêncio M, Dechering KJ, Heussler VT, Pain A, Wilder BK, Roestenberg M, Janse CJ. Franke-Fayard B, et al. Among authors: geurten fja. NPJ Vaccines. 2022 Nov 4;7(1):139. doi: 10.1038/s41541-022-00558-x. NPJ Vaccines. 2022. PMID: 36333336 Free PMC article.
Single immunization with genetically attenuated Pf∆mei2 (GA2) parasites by mosquito bite in controlled human malaria infection: a placebo-controlled randomized trial.
Roozen GVT, van Schuijlenburg R, Hensen ADO, Koopman JPR, Lamers OAC, Geurten FJA, Sijtsma JC, Baalbergen E, Janse JJ, Chevalley-Maurel S, Naar CM, Bezemer S, Kroeze H, van de Stadt HJF, de Visser B, Meij P, Tihaya MS, Colstrup E, Iliopoulou E, de Bes-Roeleveld HM, Wessels E, van der Stoep MYEC, Janse CJ, Murugan R, Franke-Fayard BMD, Roestenberg M. Roozen GVT, et al. Among authors: geurten fja. Nat Med. 2025 Jan;31(1):218-222. doi: 10.1038/s41591-024-03347-2. Epub 2025 Jan 3. Nat Med. 2025. PMID: 39753962 Free PMC article. Clinical Trial.
Safety and Efficacy of Immunization with a Late-Liver-Stage Attenuated Malaria Parasite.
Lamers OAC, Franke-Fayard BMD, Koopman JPR, Roozen GVT, Janse JJ, Chevalley-Maurel SC, Geurten FJA, de Bes-Roeleveld HM, Iliopoulou E, Colstrup E, Wessels E, van Gemert GJ, van de Vegte-Bolmer M, Graumans W, Stoter TR, Mordmüller BG, Houlder EL, Bousema T, Murugan R, McCall MBB, Janse CJ, Roestenberg M. Lamers OAC, et al. Among authors: geurten fja. N Engl J Med. 2024 Nov 21;391(20):1913-1923. doi: 10.1056/NEJMoa2313892. N Engl J Med. 2024. PMID: 39565990 Clinical Trial.