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323 results

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Page 1
Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis.
Shi B, Wang W, Korman B, Kai L, Wang Q, Wei J, Bale S, Marangoni RG, Bhattacharyya S, Miller S, Xu D, Akbarpour M, Cheresh P, Proccissi D, Gursel D, Espindola-Netto JM, Chini CCS, de Oliveira GC, Gudjonsson JE, Chini EN, Varga J. Shi B, et al. Among authors: gudjonsson je. iScience. 2020 Dec 7;24(1):101902. doi: 10.1016/j.isci.2020.101902. eCollection 2021 Jan 22. iScience. 2020. PMID: 33385109 Free PMC article.
Reduced SPAG17 Expression in Systemic Sclerosis Triggers Myofibroblast Transition and Drives Fibrosis.
Sapao P, Roberson EDO, Shi B, Assassi S, Skaug B, Lee F, Naba A, Perez White BE, Córdova-Fletes C, Tsou PS, Sawalha AH, Gudjonsson JE, Ma F, Verma P, Bhattacharyya D, Carns M, Strauss JF 3rd, Sicard D, Tschumperlin DJ, Champer MI, Campagnola PJ, Teves ME, Varga J. Sapao P, et al. Among authors: gudjonsson je. J Invest Dermatol. 2023 Feb;143(2):284-293. doi: 10.1016/j.jid.2022.08.052. Epub 2022 Sep 15. J Invest Dermatol. 2023. PMID: 36116512 Free PMC article.
Senescent Cells Accumulate in Systemic Sclerosis Skin.
Shi B, Tsou PS, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. Shi B, et al. Among authors: gudjonsson je. J Invest Dermatol. 2023 Apr;143(4):661-664.e5. doi: 10.1016/j.jid.2022.09.652. Epub 2022 Sep 30. J Invest Dermatol. 2023. PMID: 36191640 Free PMC article. No abstract available.
Pansclerotic morphea is characterized by IFN-γ responses priming dendritic cell fibroblast crosstalk to promote fibrosis.
Xing E, Ma F, Wasikowski R, Billi AC, Gharaee-Kermani M, Fox J, Dobry C, Victory A, Sarkar MK, Xing X, Plazyo O, Chen HW, Barber G, Jacobe H, Tsou PS, Modlin RL, Varga J, Kahlenberg JM, Tsoi LC, Gudjonsson JE, Khanna D. Xing E, et al. Among authors: gudjonsson je. JCI Insight. 2023 Aug 22;8(16):e171307. doi: 10.1172/jci.insight.171307. JCI Insight. 2023. PMID: 37471168 Free PMC article.
Significance of stress keratin expression in normal and diseased epithelia.
Cohen E, Johnson CN, Wasikowski R, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE, Coulombe PA. Cohen E, et al. Among authors: gudjonsson je. iScience. 2024 Jan 5;27(2):108805. doi: 10.1016/j.isci.2024.108805. eCollection 2024 Feb 16. iScience. 2024. PMID: 38299111 Free PMC article.
HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling.
Uppala R, Sarkar MK, Young KZ, Ma F, Vemulapalli P, Wasikowski R, Plazyo O, Swindell WR, Maverakis E, Gharaee-Kermani M, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE. Uppala R, et al. Among authors: gudjonsson je. iScience. 2024 Jan 23;27(2):108986. doi: 10.1016/j.isci.2024.108986. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327798 Free PMC article.
Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis.
Muraoka S, Brodie WD, Mattichak MN, Gurrea-Rubio M, Ikari Y, Foster C, Amin MA, Khanna N, Amin H, Campbell PL, Vichaikul S, Model EN, Omara MM, Petrovski S, Kozicki K, Amarista C, Webber A, Ali M, Palisoc PJ, Hervoso J, Ruth JH, Tsoi LC, Varga J, Gudjonsson JE, Khanna D, Fox DA, Tsou PS. Muraoka S, et al. Among authors: gudjonsson je. Arthritis Rheumatol. 2025 Jan;77(1):80-91. doi: 10.1002/art.42973. Epub 2024 Sep 18. Arthritis Rheumatol. 2025. PMID: 39175116 Free PMC article.
Systems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
Ma F, Tsou PS, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Ma F, et al. Among authors: gudjonsson je. Nat Commun. 2024 Jan 3;15(1):210. doi: 10.1038/s41467-023-44645-6. Nat Commun. 2024. PMID: 38172207 Free PMC article.
323 results