Maekawa M - Search Results

1

Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1'-Hydroxylation and Testosterone 6β-Hydroxylation.

Kumondai M, Gutiérrez Rico EM, Hishinuma E, Ueda A, Saito S, Saigusa D, Tadaka S, Kinoshita K, Nakayoshi T, Oda A, Abe A, Maekawa M, Mano N, Hirasawa N, Hiratsuka M. Kumondai M, et al. Among authors: maekawa m. Drug Metab Dispos. 2021 Mar;49(3):212-220. doi: 10.1124/dmd.120.000261. Epub 2020 Dec 31. Drug Metab Dispos. 2021. PMID: 33384383

2

An efficient synthesis of 4α- and 4β-hydroxy- 7-dehydrocholesterol, biomarkers for patients with and animal models of the Smith-Lemli-Opitz syndrome.

Kawamoto H, Ohmori Y, Maekawa M, Shimada M, Mano N, Iida T. Kawamoto H, et al. Among authors: maekawa m. Chem Phys Lipids. 2013 Oct-Nov;175-176:73-8. doi: 10.1016/j.chemphyslip.2013.07.004. Epub 2013 Aug 3. Chem Phys Lipids. 2013. PMID: 23920082

3

Tandem mass spectrometric characterization of bile acids and steroid conjugates based on low-energy collision-induced dissociation.

Maekawa M, Shimada M, Iida T, Goto J, Mano N. Maekawa M, et al. Steroids. 2014 Feb;80:80-91. doi: 10.1016/j.steroids.2013.11.016. Epub 2013 Dec 1. Steroids. 2014. PMID: 24296272

4

A quantitative HPLC-UV method for determination of serum sorafenib and sorafenib N-oxide and its application in hepatocarcinoma patients.

Shimada M, Okawa H, Maejima T, Yanagi T, Hisamichi K, Matsuura M, Akasaka K, Tsuchiya M, Kondo Y, Shimosegawa T, Mori M, Maekawa M, Suzuki H, Mano N. Shimada M, et al. Among authors: maekawa m. Tohoku J Exp Med. 2014 Jun;233(2):103-12. doi: 10.1620/tjem.233.103. Tohoku J Exp Med. 2014. PMID: 24872323 Free article.

5

Functional characterization of 21 CYP2C19 allelic variants for clopidogrel 2-oxidation.

Takahashi M, Saito T, Ito M, Tsukada C, Katono Y, Hosono H, Maekawa M, Shimada M, Mano N, Oda A, Hirasawa N, Hiratsuka M. Takahashi M, et al. Among authors: maekawa m. Pharmacogenomics J. 2015 Feb;15(1):26-32. doi: 10.1038/tpj.2014.30. Epub 2014 Jul 8. Pharmacogenomics J. 2015. PMID: 25001882

6

Focused metabolomics using liquid chromatography/electrospray ionization tandem mass spectrometry for analysis of urinary conjugated cholesterol metabolites from patients with Niemann-Pick disease type C and 3β-hydroxysteroid dehydrogenase deficiency.

Maekawa M, Shimada M, Ohno K, Togawa M, Nittono H, Iida T, Hofmann AF, Goto J, Yamaguchi H, Mano N. Maekawa M, et al. Ann Clin Biochem. 2015 Sep;52(Pt 5):576-87. doi: 10.1177/0004563214568871. Epub 2015 Jan 9. Ann Clin Biochem. 2015. PMID: 25575700

7

Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6α-hydroxylation and amodiaquine N-deethylation.

Tsukada C, Saito T, Maekawa M, Mano N, Oda A, Hirasawa N, Hiratsuka M. Tsukada C, et al. Among authors: maekawa m. Drug Metab Pharmacokinet. 2015 Oct;30(5):366-73. doi: 10.1016/j.dmpk.2015.07.003. Epub 2015 Jul 31. Drug Metab Pharmacokinet. 2015. PMID: 26427316

8

Monitoring Serum Levels of Sorafenib and Its N-Oxide Is Essential for Long-Term Sorafenib Treatment of Patients with Hepatocellular Carcinoma.

Shimada M, Okawa H, Kondo Y, Maejima T, Kataoka Y, Hisamichi K, Maekawa M, Matsuura M, Jin Y, Mori M, Suzuki H, Shimosegawa T, Mano N. Shimada M, et al. Among authors: maekawa m. Tohoku J Exp Med. 2015 Nov;237(3):173-82. doi: 10.1620/tjem.237.173. Tohoku J Exp Med. 2015. PMID: 26477611 Free article.

9

Identification of Two Sulfated Cholesterol Metabolites Found in the Urine of a Patient with Niemann-Pick Disease Type C as Novel Candidate Diagnostic Markers.

Maekawa M, Omura K, Sekiguchi S, Iida T, Saigusa D, Yamaguchi H, Mano N. Maekawa M, et al. Mass Spectrom (Tokyo). 2016;5(2):S0053. doi: 10.5702/massspectrometry.S0053. Epub 2016 Nov 25. Mass Spectrom (Tokyo). 2016. PMID: 27900236 Free PMC article.

10

Functional Characterization of 34 CYP2A6 Allelic Variants by Assessment of Nicotine C-Oxidation and Coumarin 7-Hydroxylation Activities.

Hosono H, Kumondai M, Maekawa M, Yamaguchi H, Mano N, Oda A, Hirasawa N, Hiratsuka M. Hosono H, et al. Among authors: maekawa m. Drug Metab Dispos. 2017 Mar;45(3):279-285. doi: 10.1124/dmd.116.073494. Epub 2016 Dec 14. Drug Metab Dispos. 2017. PMID: 27974382

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