Jiang X - Search Results

1

From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis.

Jiang BE, Jiang X, Zhang Q, Liang Q, Qiu ZL, Sun XB, Yang JJ, Chen S, Yi C, Chai X, Liu M, Yu LF, Lu W, Zhang HK. Jiang BE, et al. Among authors: jiang x. J Med Chem. 2021 Jan 14;64(1):385-403. doi: 10.1021/acs.jmedchem.0c01023. Epub 2020 Dec 31. J Med Chem. 2021. PMID: 33382613

2

The antiparasitic drug, potassium antimony tartrate, inhibits tumor angiogenesis and tumor growth in nonsmall-cell lung cancer.

Wang B, Yu W, Guo J, Jiang X, Lu W, Liu M, Pang X. Wang B, et al. Among authors: jiang x. J Pharmacol Exp Ther. 2015 Jan;352(1):129-38. doi: 10.1124/jpet.114.218644. Epub 2014 Oct 28. J Pharmacol Exp Ther. 2015. PMID: 25352499

3

Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis.

Lu W, Yao X, Ouyang P, Dong N, Wu D, Jiang X, Wu Z, Zhang C, Xu Z, Tang Y, Zou S, Liu M, Li J, Zeng M, Lin P, Cheng F, Huang J. Lu W, et al. Among authors: jiang x. J Med Chem. 2017 Mar 9;60(5):1817-1828. doi: 10.1021/acs.jmedchem.6b01507. Epub 2017 Feb 28. J Med Chem. 2017. PMID: 28218840

4

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis.

Zhang W, Lun S, Wang SH, Jiang XW, Yang F, Tang J, Manson AL, Earl AM, Gunosewoyo H, Bishai WR, Yu LF. Zhang W, et al. J Med Chem. 2018 Feb 8;61(3):791-803. doi: 10.1021/acs.jmedchem.7b01319. Epub 2018 Jan 29. J Med Chem. 2018. PMID: 29328655

5

Repurposing sertraline sensitizes non-small cell lung cancer cells to erlotinib by inducing autophagy.

Jiang X, Lu W, Shen X, Wang Q, Lv J, Liu M, Cheng F, Zhao Z, Pang X. Jiang X, et al. JCI Insight. 2018 Jun 7;3(11):e98921. doi: 10.1172/jci.insight.98921. eCollection 2018 Jun 7. JCI Insight. 2018. PMID: 29875309 Free PMC article.

6

Design, synthesis, and biological evaluations of phenylpropiolic acid derivatives as novel GPR40 agonists.

Jiang XW, Jiang BE, Liu H, Liu ZT, Hu LL, Liu M, Lu W, Zhang HK. Jiang XW, et al. Eur J Med Chem. 2018 Oct 5;158:123-133. doi: 10.1016/j.ejmech.2018.08.075. Epub 2018 Aug 31. Eur J Med Chem. 2018. PMID: 30212763

7

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling.

Huang Y, Fang J, Lu W, Wang Z, Wang Q, Hou Y, Jiang X, Reizes O, Lathia J, Nussinov R, Eng C, Cheng F. Huang Y, et al. Among authors: jiang x. Cell Chem Biol. 2019 Aug 15;26(8):1143-1158.e6. doi: 10.1016/j.chembiol.2019.05.004. Epub 2019 Jun 6. Cell Chem Biol. 2019. PMID: 31178408 Free PMC article.

8

Celastrol is a novel selective agonist of cannabinoid receptor 2 with anti-inflammatory and anti-fibrotic activity in a mouse model of systemic sclerosis.

Jiang X, Chen S, Zhang Q, Yi C, He J, Ye X, Liu M, Lu W. Jiang X, et al. Phytomedicine. 2020 Feb;67:153160. doi: 10.1016/j.phymed.2019.153160. Epub 2019 Dec 26. Phytomedicine. 2020. PMID: 31901889

9

Antiallergic drug desloratadine as a selective antagonist of 5HT_2A receptor ameliorates pathology of Alzheimer's disease model mice by improving microglial dysfunction.

Lu J, Zhang C, Lv J, Zhu X, Jiang X, Lu W, Lu Y, Tang Z, Wang J, Shen X. Lu J, et al. Among authors: jiang x. Aging Cell. 2021 Jan;20(1):e13286. doi: 10.1111/acel.13286. Epub 2020 Dec 24. Aging Cell. 2021. PMID: 33369003 Free PMC article.

10

Design, synthesis, and biological evaluations of 5-aryl-pyrazole-3-carboxamide derivatives as selective CB2 receptor agonists for the treatment of colitis.

Jiang BE, He Y, Chen J, Jiang XW, Qiu ZL, Liang QW, Gao XL, Zhang HK, Tian HG, Liu MY, Lu WQ, Yu LF. Jiang BE, et al. Eur J Med Chem. 2025 Feb 5;283:117117. doi: 10.1016/j.ejmech.2024.117117. Epub 2024 Dec 2. Eur J Med Chem. 2025. PMID: 39653620

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