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A cross-industry collaboration to assess if acute oral toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling.
Bercu J, Masuda-Herrera MJ, Trejo-Martin A, Hasselgren C, Lord J, Graham J, Schmitz M, Milchak L, Owens C, Lal SH, Robinson RM, Whalley S, Bellion P, Vuorinen A, Gromek K, Hawkins WA, van de Gevel I, Vriens K, Kemper R, Naven R, Ferrer P, Myatt GJ. Bercu J, et al. Among authors: schmitz m. Regul Toxicol Pharmacol. 2021 Mar;120:104843. doi: 10.1016/j.yrtph.2020.104843. Epub 2020 Dec 17. Regul Toxicol Pharmacol. 2021. PMID: 33340644 Free PMC article.
Corrigendum to a cross-industry collaboration to assess if acute toxicity (Q)SAR models are fit-for-purpose for GHS classification and labelling. Regulatory toxicology and pharmacology (2021) 104843.
Bercu J, Masuda Herrera MJ, Trejo-Martin A, Hasselgren C, Lord J, Graham J, Schmitz M, Milchak L, Owens C, Lal SH, Robinson RM, Whalley S, Bellion P, Vuorinen A, Gromek K, Hawkins WA, Van de Gevel I, Vriens K, Kemper R, Naven R, Ferrer P, Myatt GJ. Bercu J, et al. Among authors: schmitz m. Regul Toxicol Pharmacol. 2022 Jun;131:105165. doi: 10.1016/j.yrtph.2022.105165. Epub 2022 Apr 23. Regul Toxicol Pharmacol. 2022. PMID: 35474000 Free PMC article. No abstract available.
An Evaluation of the Occupational Health Hazards of Peptide Couplers.
Graham JC, Trejo-Martin A, Chilton ML, Kostal J, Bercu J, Beutner GL, Bruen US, Dolan DG, Gomez S, Hillegass J, Nicolette J, Schmitz M. Graham JC, et al. Among authors: schmitz m. Chem Res Toxicol. 2022 Jun 20;35(6):1011-1022. doi: 10.1021/acs.chemrestox.2c00031. Epub 2022 May 9. Chem Res Toxicol. 2022. PMID: 35532537 Free PMC article.
Safety assessment of protein A and derivation of a parenteral health-based exposure limit.
Graham JC, Anand SS, Bercu J, Besenhofer L, de Zafra C, Feng Y, Fisher C, Hillegass J, Hutchinson R, Jolly R, Moudgal C, Nicholas T, Olszova D, Schmitz M, Semmelmann F. Graham JC, et al. Among authors: schmitz m. Regul Toxicol Pharmacol. 2024 Nov;153:105700. doi: 10.1016/j.yrtph.2024.105700. Epub 2024 Sep 6. Regul Toxicol Pharmacol. 2024. PMID: 39243930 Free article.
Comprehensive Extractables and Leachables Sensitization Analysis and Practical Application of a Risk-Based Approach to Sensitization Assessment for Parenteral Drug Products.
Parris P, Whelan G, Chilton ML, Beaumont C, Burild A, Bruen U, Callis C, Graham J, Kovalova N, Martin EA, Masuda-Herrera M, Worsøe C, Alami A, Bercu J, Doron D, Dusenbury K, Fu Q, Griffin T, Hillegass J, Johann E, Koenig A, Macho N, Martirosyan A, Oded K, Guarch CP, Schmitz M, Stanard B, Tien E, Udovic E, Xu H, Cruz MT, Nagao L. Parris P, et al. Among authors: schmitz m. Regul Toxicol Pharmacol. 2025 Jan 28:105776. doi: 10.1016/j.yrtph.2025.105776. Online ahead of print. Regul Toxicol Pharmacol. 2025. PMID: 39884453
Combining T cell receptor sequencing and transcriptomics to characterize tissue-resident T cells from human gut biopsies.
Goel M, Steinberg-Bains K, Eugster A, Wehner R, Tunger A, Reinhardt S, Sharma V, Rost F, Schmitz M, Schmelz R, Zeissig S, Rachner TD, Bornhäuser M, Bonifacio E, Link-Rachner CS. Goel M, et al. Among authors: schmitz m. Biochem Biophys Res Commun. 2025 Feb 16;749:151353. doi: 10.1016/j.bbrc.2025.151353. Epub 2025 Jan 16. Biochem Biophys Res Commun. 2025. PMID: 39837221
Resetting of the Human Circadian Melatonin Rhythm by Ambient Hypoxia.
Post TE, De Gioannis R, Schmitz J, Wittkowski M, Schäper TM, Wrobeln A, Fandrey J, Schmitz MT, Takahashi JS, Jordan J, Elmenhorst EM, Aeschbach D. Post TE, et al. Among authors: schmitz mt. J Pineal Res. 2025 Jan;77(1):e70029. doi: 10.1111/jpi.70029. J Pineal Res. 2025. PMID: 39821326 Free PMC article. Clinical Trial.
1,472 results