Huwyler J - Search Results

1

Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2.

Bachmann F, Duthaler U, Meyer Zu Schwabedissen HE, Puchkov M, Huwyler J, Haschke M, Krähenbühl S. Bachmann F, et al. Among authors: huwyler j. Clin Pharmacol Ther. 2021 Jun;109(6):1505-1516. doi: 10.1002/cpt.2141. Epub 2021 Jan 19. Clin Pharmacol Ther. 2021. PMID: 33336382 Free PMC article.

2

Targeting of daunomycin using biotinylated immunoliposomes: pharmacokinetics, tissue distribution and in vitro pharmacological effects.

Schnyder A, Krähenbühl S, Drewe J, Huwyler J. Schnyder A, et al. Among authors: huwyler j. J Drug Target. 2005 Jun;13(5):325-35. doi: 10.1080/10611860500206674. J Drug Target. 2005. PMID: 16199376

3

Induction of cytochrome P450 3A4 and P-glycoprotein by the isoxazolyl-penicillin antibiotic flucloxacillin.

Huwyler J, Wright MB, Gutmann H, Drewe J. Huwyler J, et al. Curr Drug Metab. 2006 Feb;7(2):119-26. doi: 10.2174/138920006775541534. Curr Drug Metab. 2006. PMID: 16472102

4

Tumor targeting using liposomal antineoplastic drugs.

Huwyler J, Drewe J, Krähenbuhl S. Huwyler J, et al. Int J Nanomedicine. 2008;3(1):21-9. Int J Nanomedicine. 2008. PMID: 18488413 Free PMC article. Review.

5

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies.

Poller B, Gutmann H, Krähenbühl S, Weksler B, Romero I, Couraud PO, Tuffin G, Drewe J, Huwyler J. Poller B, et al. Among authors: huwyler j. J Neurochem. 2008 Dec;107(5):1358-68. doi: 10.1111/j.1471-4159.2008.05730.x. J Neurochem. 2008. PMID: 19013850 Free article.

6

Regulation of BCRP (ABCG2) and P-glycoprotein (ABCB1) by cytokines in a model of the human blood-brain barrier.

Poller B, Drewe J, Krähenbühl S, Huwyler J, Gutmann H. Poller B, et al. Among authors: huwyler j. Cell Mol Neurobiol. 2010 Jan;30(1):63-70. doi: 10.1007/s10571-009-9431-1. Epub 2009 Jul 23. Cell Mol Neurobiol. 2010. PMID: 19629677

7

Efficacy, safety and pharmacokinetics of 1,2,4-trioxolane OZ78 against an experimental infection with Fasciola hepatica in sheep.

Keiser J, Kirchhofer C, Haschke M, Huwyler J, Dong Y, Vennerstrom JL, Vanhoff K, Kaminsky R, Malikides N. Keiser J, et al. Among authors: huwyler j. Vet Parasitol. 2010 Oct 29;173(3-4):228-35. doi: 10.1016/j.vetpar.2010.06.031. Epub 2010 Jun 25. Vet Parasitol. 2010. PMID: 20674178

8

Development and validation of a liquid chromatography and ion spray tandem mass spectrometry method for the quantification of artesunate, artemether and their major metabolites dihydroartemisinin and dihydroartemisinin-glucuronide in sheep plasma.

Duthaler U, Keiser J, Huwyler J. Duthaler U, et al. Among authors: huwyler j. J Mass Spectrom. 2011 Feb;46(2):172-81. doi: 10.1002/jms.1883. Epub 2011 Jan 24. J Mass Spectrom. 2011. PMID: 21259399

9

The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA ("ecstasy") in humans.

Hysek CM, Simmler LD, Ineichen M, Grouzmann E, Hoener MC, Brenneisen R, Huwyler J, Liechti ME. Hysek CM, et al. Among authors: huwyler j. Clin Pharmacol Ther. 2011 Aug;90(2):246-55. doi: 10.1038/clpt.2011.78. Epub 2011 Jun 15. Clin Pharmacol Ther. 2011. PMID: 21677639 Clinical Trial.

10

Evaluation of the pharmacokinetic profile of artesunate, artemether and their metabolites in sheep naturally infected with Fasciola hepatica.

Duthaler U, Huwyler J, Rinaldi L, Cringoli G, Keiser J. Duthaler U, et al. Among authors: huwyler j. Vet Parasitol. 2012 May 25;186(3-4):270-80. doi: 10.1016/j.vetpar.2011.11.076. Epub 2011 Dec 6. Vet Parasitol. 2012. PMID: 22206644

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