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Discovery of highly potent heme-displacing IDO1 inhibitors based on a spirofused bicyclic scaffold.
Bioorg Med Chem Lett. 2021 Feb 1;33:127738. doi: 10.1016/j.bmcl.2020.127738. Epub 2020 Dec 11.
Bioorg Med Chem Lett. 2021.
PMID: 33316404
Discovery of Hydroxyamidine Based Inhibitors of IDO1 for Cancer Immunotherapy with Reduced Potential for Glucuronidation.
Steeneck C, Kinzel O, Anderhub S, Hornberger M, Pinto S, Morschhaeuser B, Braun F, Kleymann G, Hoffmann T.
Steeneck C, et al. Among authors: morschhaeuser b.
ACS Med Chem Lett. 2020 Jan 27;11(2):179-187. doi: 10.1021/acsmedchemlett.9b00572. eCollection 2020 Feb 13.
ACS Med Chem Lett. 2020.
PMID: 32071686
Free PMC article.
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Discovery and optimization of substituted oxalamides as novel heme-displacing IDO1 inhibitors.
Steeneck C, Kinzel O, Anderhub S, Hornberger M, Pinto S, Morschhaeuser B, Albers M, Sonnek C, Czekańska M, Hoffmann T.
Steeneck C, et al. Among authors: morschhaeuser b.
Bioorg Med Chem Lett. 2021 Feb 1;33:127744. doi: 10.1016/j.bmcl.2020.127744. Epub 2020 Dec 15.
Bioorg Med Chem Lett. 2021.
PMID: 33333163
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