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Targeting transcriptional regulation of SARS-CoV-2 entry factors ACE2 and TMPRSS2.
Qiao Y, Wang XM, Mannan R, Pitchiaya S, Zhang Y, Wotring JW, Xiao L, Robinson DR, Wu YM, Tien JC, Cao X, Simko SA, Apel IJ, Bawa P, Kregel S, Narayanan SP, Raskind G, Ellison SJ, Parolia A, Zelenka-Wang S, McMurry L, Su F, Wang R, Cheng Y, Delekta AD, Mei Z, Pretto CD, Wang S, Mehra R, Sexton JZ, Chinnaiyan AM. Qiao Y, et al. Among authors: wang xm, wang s, wang r. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2021450118. doi: 10.1073/pnas.2021450118. Epub 2020 Dec 28. Proc Natl Acad Sci U S A. 2021. PMID: 33310900 Free PMC article.
Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
Asangani IA, Dommeti VL, Wang X, Malik R, Cieslik M, Yang R, Escara-Wilke J, Wilder-Romans K, Dhanireddy S, Engelke C, Iyer MK, Jing X, Wu YM, Cao X, Qin ZS, Wang S, Feng FY, Chinnaiyan AM. Asangani IA, et al. Among authors: wang x, wang s. Nature. 2014 Jun 12;510(7504):278-82. doi: 10.1038/nature13229. Epub 2014 Apr 23. Nature. 2014. PMID: 24759320 Free PMC article.
Role of BET proteins in castration-resistant prostate cancer.
Fernandez-Salas E, Wang S, Chinnaiyan AM. Fernandez-Salas E, et al. Among authors: wang s. Drug Discov Today Technol. 2016 Mar;19:29-38. doi: 10.1016/j.ddtec.2016.07.001. Epub 2016 Jul 30. Drug Discov Today Technol. 2016. PMID: 27769354 Review.
Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.
Wang X, Qiao Y, Asangani IA, Ateeq B, Poliakov A, Cieślik M, Pitchiaya S, Chakravarthi BVSK, Cao X, Jing X, Wang CX, Apel IJ, Wang R, Tien JC, Juckette KM, Yan W, Jiang H, Wang S, Varambally S, Chinnaiyan AM. Wang X, et al. Among authors: wang cx, wang s, wang r. Cancer Cell. 2017 Apr 10;31(4):532-548.e7. doi: 10.1016/j.ccell.2017.02.017. Epub 2017 Mar 23. Cancer Cell. 2017. PMID: 28344039 Free PMC article.
Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer.
Wang X, Qiao Y, Asangani IA, Ateeq B, Poliakov A, Cieślik M, Pitchiaya S, Chakravarthi BVSK, Cao X, Jing X, Wang CX, Apel IJ, Wang R, Tien JC, Juckette KM, Yan W, Jiang H, Wang S, Varambally S, Chinnaiyan AM. Wang X, et al. Among authors: wang cx, wang s, wang r. Cancer Cell. 2017 Jun 12;31(6):844-847. doi: 10.1016/j.ccell.2017.05.001. Cancer Cell. 2017. PMID: 28609659 Free article. No abstract available.
Characterizing the Therapeutic Potential of a Potent BET Degrader in Merkel Cell Carcinoma.
Choi JE, Verhaegen ME, Yazdani S, Malik R, Harms PW, Mangelberger D, Tien J, Cao X, Wang Y, Cieślik M, Gurkan J, Yazdani M, Jing X, Juckette K, Su F, Wang R, Zhou B, Apel IJ, Wang S, Dlugosz AA, Chinnaiyan AM. Choi JE, et al. Among authors: wang y, wang s, wang r. Neoplasia. 2019 Mar;21(3):322-330. doi: 10.1016/j.neo.2019.01.003. Epub 2019 Feb 21. Neoplasia. 2019. PMID: 30797188 Free PMC article.
Functional and Mechanistic Interrogation of BET Bromodomain Degraders for the Treatment of Metastatic Castration-resistant Prostate Cancer.
Kregel S, Malik R, Asangani IA, Wilder-Romans K, Rajendiran T, Xiao L, Vo JN, Soni T, Cieslik M, Fernadez-Salas E, Zhou B, Cao X, Speers C, Wang S, Chinnaiyan AM. Kregel S, et al. Among authors: wang s. Clin Cancer Res. 2019 Jul 1;25(13):4038-4048. doi: 10.1158/1078-0432.CCR-18-3776. Epub 2019 Mar 27. Clin Cancer Res. 2019. PMID: 30918020 Free PMC article.
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